Title: | Investigations into the effect on rats of volatile organic compounds released from the set of building and finishing materials |
Author(s): | Wiglusz R; Jarnuszkiewicz I; Delag G; Dubicka J; Galuszko E; Wolska L; Winnicka A; Hac E; |
Address: | "Department of Toxicology, Institute of Maritime and Tropical Medicine, Gdynia" |
Journal Title: | Bull Inst Marit Trop Med Gdynia |
ISSN/ISBN: | 0324-8542 (Print) 0324-8542 (Linking) |
Abstract: | "White, male Wistar rats were exposed continuously in chamber during 3 months on volatile organic compounds emitted from set of building and finishing materials used in living areas on ship. The air contamination was checked. The following tests for determination of combined toxic effects were performed: functional activity, the body and organ weights, basic hematological determinations, serum enzyme activity (GOT, GPT, AP, LAP, LDH), serum concentrations of protein, urea, creatinine, bilirubin, lipids, cholesterol, triglycerides, and in the liver mitochondria Mg+2(-)-ATPase, concentration of cholesterol, phospholipids, and liver function after loading with benzoate. After 3 months of the exposure we observed changes in AP and LDH activities, and decrease of the concentration of serum triglycerides" |
Keywords: | "Acetates/adverse effects Air Pollution/adverse effects Animals Construction Materials/*adverse effects *Environmental Exposure Formaldehyde/adverse effects Hazardous Substances/adverse effects L-Lactate Dehydrogenase/blood Leukocytes, Mononuclear/drug eff;" |
Notes: | "MedlineWiglusz, R Jarnuszkiewicz, I Delag, G Dubicka, J Galuszko, E Wolska, L Winnicka, A Hac, E eng Poland 1988/01/01 Bull Inst Marit Trop Med Gdynia. 1988; 39(3-4):205-14" |