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Ecotoxicol Environ Saf

Title:		Air pollution-related asthma profiles among children/adolescents: A multi-group latent class analysis
Author(s):		Shakerkhatibi M; Benis KZ; Asghari-Jafarabadi M; Sadeghi-Bazarghani H; Allahverdipour H; Oskouei DS; Fatehifar E; Farajzadeh M; Yadeghari A; Ansarin K; Jafari R; Zakeri A; Moshashaei P; Behnami A;
Address:		"Health and Environment Research Center, Tabriz University of Medical Sciences, Tabriz, Iran. Department of Chemical and Biological Engineering, University of Saskatchewan, Saskatoon, SK, Canada. Center for the Development of Interdisciplinary Research in Islamic Sciences and Health Sciences, Tabriz University of Medical Sciences, Tabriz, Iran; Department of Statistics and Epidemiology, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran. Electronic address: asgharimo@tbzmed.ac.ir. Road Traffic Injury Research Center, Tabriz University of Medical Sciences, Tabriz, Iran. Psychiatry and Behavioral Sciences Research Center, Tabriz University of Medical Sciences, Tabriz, Iran. Department of Neurology, Tabriz University of Medical Sciences, Tabriz, Iran. Department of Chemical Engineering, Sahand University of Technology, Tabriz, Iran. Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran. Department of Analytical Chemistry, Faculty of Chemistry, University of Tabriz, Tabriz, Iran. Tuberculosis and Lung Disease Research Center, Tabriz University of Medical Sciences, Tabriz, Iran. National Public Health Management Center, Tabriz University of Medical Sciences, Tabriz, Iran"
Journal Title:		Ecotoxicol Environ Saf
Year:		2021
Volume:		20210520
Issue:
Page Number:		112344 -
DOI:		10.1016/j.ecoenv.2021.112344
ISSN/ISBN:		1090-2414 (Electronic) 0147-6513 (Linking)
Abstract:		"BACKGROUND: This study aimed to investigate the asthma profile among children/adolescents and the relationship of the prevalence of air pollution profiles using latent class analysis (LCA). OBJECTIVES: In this cross-sectional study, a case rural community was selected in an industrial area, and two rural control communities were selected in unexposed areas. METHODS: Hourly concentrations of PM(10), SO(2), NO(2,) and total volatile organic compounds were obtained from the records of a fixed air quality monitoring station, and the concentrations of benzene, toluene, xylenes styrene were measured during six campaigns. Asthma data was collected using the International Study of Asthma and Allergies in Childhood in 7-18 years old children/adolescents. The modeling was conducted using LCA. RESULTS: A higher amount of air pollution indices were observed in the case than both control communities. LCA divided the participants into three clusters; 'healthy' (92.8%), 'moderate' (2.8%), and 'severe' (4.4%). A higher probability of severe asthma (6.8%) was observed in the case than control communities (2.6% and 1.8%). Additionally, after adjusting for possible confounders, the odds of asthma was lower in the control communities than the case in both moderate and sever classes (Odds Ratios in the range of 0.135-0.697). CONCLUSIONS: This study indicates asthma profiles of children/adolescents and the higher prevalence of severe class in the area, explaining the possible effect of air pollution"
Keywords:		Adolescent Air Pollutants/analysis Air Pollution/analysis/*statistics & numerical data Asthma/*epidemiology Child Cross-Sectional Studies Humans Industry Latent Class Analysis Male Particulate Matter/analysis Prevalence Rural Population Volatile Organic C;
Notes:		"MedlineShakerkhatibi, Mohammad Benis, Khaled Zoroufchi Asghari-Jafarabadi, Mohammad Sadeghi-Bazarghani, Homayon Allahverdipour, Hamid Oskouei, Daryoush Savadi Fatehifar, Esmaeil Farajzadeh, Masoumeh Yadeghari, Adeleh Ansarin, Khalil Jafari, Rozita Zakeri, Akram Moshashaei, Parisa Behnami, Ali eng Netherlands 2021/05/24 Ecotoxicol Environ Saf. 2021 Aug; 219:112344. doi: 10.1016/j.ecoenv.2021.112344. Epub 2021 May 20"