| Title: | Development of Sustainable Chemistry in Madagascar: Example of the Valuation of CNSL and the Use of Chromones as an Attractant for Mosquitoes |
| Author(s): | Ranarijaona MM; Rambala Rakotomena NAH; Andrianjafy MT; Ramiharimanana FD; Herinirina LC; Ramarosandratana NH; Briou B; Fajardie P; Mavingui P; Metay E; Ramanandraibe VV; Lemaire M; |
| Address: | "International Associated Laboratory, Faculty of Sciences, IST Campus, University of Antananarivo-Lyon, Ampasapito, Antananarivo 101, Madagascar. Unite Mixte Processus Infectieux en Milieu Insulaire Tropical, Plateforme Technologique CYROI, University of Reunion, Sainte Clotilde, 97490 La Reunion, France. Orpia Innovation, Centre National de la Recherche Scientifique CNRS Batiment Balard, 34000 Montpellier, France. Institut de Chimie et Biochimie Moleculaires et Supramoleculaires (ICBMS), University of Claude Bernard Lyon 1/CNRS, 1 rue Victor Grignard, 69100 Villeurbanne, France" |
| DOI: | 10.3390/molecules26247625 |
| ISSN/ISBN: | 1420-3049 (Electronic) 1420-3049 (Linking) |
| Abstract: | "This article describes a part of the results obtained from the cooperation between the University of Lyon1 (France) and the University of Antananarivo (Madagascar). It shows (among others) that useful research can be carried out in developing countries of the tropics if their social, technical, and economic conditions are taken into account. The concepts and methods associated with so-called 'green chemistry' are particularly appropriated for this purpose. To illustrate this approach, two examples are shown. The first deals with industrial ecology and concerns waste transformation from the production of cashew nut into an amphiphilic product, oxyacetic derivatives. This product was obtained with a high yield and in a single step reaction. It exhibited an important surfactant property similar to those of the main fossil-based ones but with a much lower ecological impact. The second talks about chemical ecology as an alternative to insecticides and used to control dangerous mosquito populations. New substituted chromones were synthesized and showed biological activities toward Aedes albopictus mosquito species. Strong repellent properties were recorded for some alkoxylated products if others had a significant attractant effect (Kairomone) depending on their stereochemistry and the length of the alkyl chain" |
| Keywords: | Aedes/*physiology Animals *Chromones/chemical synthesis/chemistry/pharmacology *Insect Repellents/chemical synthesis/chemistry/pharmacology Madagascar Aedes albopictus attractant cashew nut shell liquid chemical ecology chromone industrial ecology oxyacet; |
| Notes: | "MedlineRanarijaona, Miarintsoa Michaele Rambala Rakotomena, Ny Aina Harivony Andrianjafy, Mbolatiana Tovo Ramiharimanana, Fenia Diane Herinirina, Lydia Clarisse Ramarosandratana, Niry Hasinandrianina Briou, Benoit Fajardie, Pauline Mavingui, Patrick Metay, Estelle Ramanandraibe, Voahangy Vestalys Lemaire, Marc eng Switzerland 2021/12/25 Molecules. 2021 Dec 16; 26(24):7625. doi: 10.3390/molecules26247625" |
