| Title: | Modulation techniques and applications in comprehensive two-dimensional gas chromatography (GC x GC) |
| Author(s): | Pursch M; Sun K; Winniford B; Cortes H; Weber A; McCabe T; Luong J; |
| Address: | "Dow Deutschland GmbH & Co. OHG, Analytical Sciences, 77836 Rheinmunster, Germany. mpursch@dow.com" |
| DOI: | 10.1007/s00216-002-1318-7 |
| ISSN/ISBN: | 1618-2642 (Print) 1618-2642 (Linking) |
| Abstract: | "More than a decade after Phillips' first published work this article reviews recent developments in comprehensive two-dimensional gas chromatography (GC x GC). Special attention is devoted to the further development and diversity of modulation devices. These include heated sweepers, cryofocused modulators, and a variety of diaphragm valve-switching strategies. It is demonstrated that all modulation approaches can be very well suited to GC x GC, depending on the particular application. Diaphragm-valve modulation is very powerful for volatile organic compounds. Slotted heater and cryofocused modulation are preferred for samples that contain non-volatile components. Applications ranging from petroleum to environmental and biological samples are illustrated. Extension of the technique to GC x GC-mass spectrometry (MS) is also discussed and trends for future research activity are pointed out" |
| Keywords: | "Chromatography, Gas/instrumentation/*methods Equipment Design Oils, Volatile/analysis Pesticides/analysis Sensitivity and Specificity Water Pollutants, Chemical/analysis;" |
| Notes: | "MedlinePursch, Matthias Sun, Kefu Winniford, Bill Cortes, Hernan Weber, Andy McCabe, Terry Luong, Jim eng Germany 2002/08/13 Anal Bioanal Chem. 2002 Jul; 373(6):356-67. doi: 10.1007/s00216-002-1318-7. Epub 2002 Jul 4" |
