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Allergy

Title:		Addressing adverse synergies between chemical and biological pollutants at schools-The 'SynAir-G' hypothesis
Author(s):		Papadopoulos NG; Akdis C; Akdis M; Damialis A; Esposito G; Fergadiotou I; Goroncy C; Guitton P; Gotua M; Erotokritou K; Jartti T; Murray C; Nenes A; Nikoletseas S; Finotto S; Pandis SN; Ramiconi V; Simpson A; Soudunsaari A; Starbrost A; Staiano M; Varriale A; Xepapadaki P; Zuberbier T; Annesi-Maesano I; SynAir GC;
Address:		"Division of Immunology, Immunity to Infection and Respiratory Medicine, School of Biological Sciences, The University of Manchester, Manchester, UK. Allergy Department, 2nd Paediatric Clinic, National and Kapodistrian University of Athens, Athens, Greece. Swiss Institute of Allergy and Asthma Research (SIAF), University of Zurich, Davos, Switzerland, Christine Kuhne-Center for Allergy Research and Education (CK-CARE), Davos, Switzerland. Department of Ecology, School of Biology, Aristotle University of Thessaloniki, Thessaloniki, Greece. Bio Check Up (BCU), Naples, Italy. INLECOM INNOVATION, Kifissia, Greece. DIN Deutsches Institut fuer Normung EV, Berlin, Germany. TEQOYA Company, Paris, France. Center for Allergy and Immunology Research (CAIR), Tbilisi, Georgia. CY.R.I.C Cyprus Research and Innovation Center Ltd, Nicosia, Cyprus. PEDEGO Research Unit, University of Oulu, Oulu, Finland. Department of Pediatrics, Oulu University Hospital, Oulu, Finland. Department of Pediatrics and Adolescent Medicine, Turku University Hospital and University of Turku, Turku, Finland. Laboratory of Atmospheric Processes and their Impacts, School of Architecture, Civil and Environmental Engineering, Swiss Institute of Technology, Lausanne, Switzerland. Computer Engineering and Informatics Department, University of Patras, Patras, Greece. Molecular Pneumology Department, University Hospital of Erlangen, Erlangen, Germany. Institute of Chemical Engineering Sciences (ICEHT), Foundation for Research and Technology Hellas (FORTH), Patras, Greece. The European Federation of Allergy and Airways Diseases Patients' Association (EFA), Brussels, Belgium. NAAVA, Helsinki, Finland. Lulea University of Technology, Lulea, Sweden. Institute of Food Science, CNR Italy, Avellino, Italy. URT-ISA, CNR at Department of Biology, University of Naples Federico II, Naples, Italy. Institute of Allergology, Charite-Universitatsmedizin Berlin, Corporate Member of Freie Universitat Berlin and Humboldt Universitat zu Berlin, Berlin, Germany. Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Allergology and Immunology, Berlin, Germany. Global Allergy & Asthma European Network of Excellence-GA2LEN, Berlin, Germany. Department of Allergic and Respiratory Disease, Institut Desbrest of Epidemiology and Public Health, University of Montpellier and INSERM, Montpellier University Hospital, Montpellier, France"
Journal Title:		Allergy
Year:		2023
Volume:		20230831
Issue:
Page Number:		-
DOI:		10.1111/all.15857
ISSN/ISBN:		1398-9995 (Electronic) 0105-4538 (Linking)
Abstract:		"While the number and types of indoor air pollutants is rising, much is suspected but little is known about the impact of their potentially synergistic interactions, upon human health. Gases, particulate matter, organic compounds but also allergens and viruses, fall within the 'pollutant' definition. Distinct populations, such as children and allergy and asthma sufferers are highly susceptible, while a low socioeconomic background is a further susceptibility factor; however, no specific guidance is available. We spend most of our time indoors; for children, the school environment is of paramount importance and potentially amenable to intervention. The interactions between some pollutant classes have been studied. However, a lot is missing with respect to understanding interactions between specific pollutants of different classes in terms of concentrations, timing and sequence, to improve targeting and upgrade standards. SynAir-G is a European Commission-funded project aiming to reveal and quantify synergistic interactions between different pollutants affecting health, from mechanisms to real life, focusing on the school setting. It will develop a comprehensive and responsive multipollutant monitoring system, advance environmentally friendly interventions, and disseminate the generated knowledge to relevant stakeholders in accessible and actionable formats. The aim of this article it to put forward the SynAir-G hypothesis, and describe its background and objectives"
Keywords:		aerobiology allergy artificial intelligence asthma biosensors children school virus volatile organic compounds;
Notes:		"PublisherPapadopoulos, Nikolaos G Akdis, Cezmi Akdis, Mubeccel Damialis, Athanasios Esposito, Giuseppina Fergadiotou, Ioana Goroncy, Christian Guitton, Pierre Gotua, Maia Erotokritou, Kleanthis Jartti, Tuomas Murray, Clare Nenes, Athanasios Nikoletseas, Sotirios Finotto, Susetta Pandis, Spyros N Ramiconi, Valeria Simpson, Angela Soudunsaari, Aki Starbrost, Anna Staiano, Maria Varriale, Antonio Xepapadaki, Paraskevi Zuberbier, Torsten Annesi-Maesano, Isabella eng 101057271/HORIZON EUROPE Health/ Review Denmark 2023/09/01 Allergy. 2023 Aug 31. doi: 10.1111/all.15857"