| Title: | "Evaluation of the photosynthetic parameters, emission of volatile organic compounds and ultrastructure of common green leafy vegetables after exposure to non-steroidal anti-inflammatory drugs (NSAIDs)" |
| Author(s): | Opris O; Ciorita A; Soran ML; Lung I; Copolovici D; Copolovici L; |
| Address: | "National Institute for Research and Development of Isotopic and Molecular Technologies, 67-103 Donat, 400293, Cluj-Napoca, Romania. Faculty of Food Engineering, Tourism and Environmental Protection and Institute of Research, Innovation and Development in Technical and Natural Sciences of 'Aurel Vlaicu' University, 2 Elena Dragoi, 310330, Arad, Romania. Faculty of Food Engineering, Tourism and Environmental Protection and Institute of Research, Innovation and Development in Technical and Natural Sciences of 'Aurel Vlaicu' University, 2 Elena Dragoi, 310330, Arad, Romania. lucian.copolovici@uav.ro" |
| DOI: | 10.1007/s10646-019-02059-5 |
| ISSN/ISBN: | 1573-3017 (Electronic) 0963-9292 (Linking) |
| Abstract: | "Understanding the effects of many essential non-steroidal anti-inflammatory drugs (NSAIDs) on plants is still limited, especially at environmentally realistic concentrations. This paper presents the influence of three of the most frequently used NSAIDs (diclofenac, ibuprofen, and naproxen) at environmentally realistic concentrations on the autochthonous green leafy vegetables: orache (Atriplex patula L.), spinach (Spinacia oleracea L.) and lettuce (Lactuca sativa L.). Our research was focused on the determination of the photosynthetic parameters, the emission rate of volatile organic compounds, and the evaluation of the ultrastructure of leaves of studied vegetables after exposure to abiotic stress induced by environmental pollutants, namely NSAIDs. The data obtained indicate a moderate reduction of foliage physiological activity as a response to the stress induced by NSAIDs to the selected green leafy vegetables. The increase of the 3-hexenal and monoterpene emission rates with increasing NSAIDs concentration could be used as a sensitive and a rapid indicator to assess the toxicity of the NSAIDs. Microscopic analysis showed that the green leafy vegetables were affected by the selected NSAIDs. In comparison to the controls, the green leafy vegetables treated with NSAIDs presented irregular growth of glandular trichomes on the surface of the adaxial side of the leaves, less stomata, cells with less cytoplasm, irregular cell walls and randomly distributed chloroplasts. Of the three NSAIDs investigated in this study, ibuprofen presented the highest influence. The results obtained in this study can be used to better estimate the impact of drugs on the environment and to improve awareness on the importance of the responsible use of drugs" |
| Keywords: | "Anti-Inflammatory Agents, Non-Steroidal/*adverse effects Atriplex/*drug effects/physiology/ultrastructure Diclofenac/adverse effects Environmental Pollutants/*adverse effects Ibuprofen/adverse effects Lettuce/*drug effects/physiology/ultrastructure Micros;" |
| Notes: | "MedlineOpris, Ocsana Ciorita, Alexandra Soran, Maria-Loredana Lung, Ildiko Copolovici, Dana Copolovici, Lucian eng 2019/06/05 Ecotoxicology. 2019 Aug; 28(6):631-642. doi: 10.1007/s10646-019-02059-5. Epub 2019 Jun 3" |
