| Title: | Air Ambulance: Antimicrobial Power of Bacterial Volatiles |
| Author(s): | Lammers A; Lalk M; Garbeva P; |
| Address: | "Department of Cellular Biochemistry and Metabolomics, University of Greifswald, 17487 Greifswald, Germany. Department of Microbial Ecology, Netherlands Institute of Ecology (NIOO-KNAW), 6708 PB Wageningen, The Netherlands" |
| DOI: | 10.3390/antibiotics11010109 |
| ISSN/ISBN: | 2079-6382 (Print) 2079-6382 (Electronic) 2079-6382 (Linking) |
| Abstract: | "We are currently facing an antimicrobial resistance crisis, which means that a lot of bacterial pathogens have developed resistance to common antibiotics. Hence, novel and innovative solutions are urgently needed to combat resistant human pathogens. A new source of antimicrobial compounds could be bacterial volatiles. Volatiles are ubiquitous produced, chemically divers and playing essential roles in intra- and interspecies interactions like communication and antimicrobial defense. In the last years, an increasing number of studies showed bioactivities of bacterial volatiles, including antibacterial, antifungal and anti-oomycete activities, indicating bacterial volatiles as an exciting source for novel antimicrobial compounds. In this review we introduce the chemical diversity of bacterial volatiles, their antimicrobial activities and methods for testing this activity. Concluding, we discuss the possibility of using antimicrobial volatiles to antagonize the antimicrobial resistance crisis" |
| Keywords: | antibacterial antibiotics antifungal antimicrobial resistance crisis chemical ecology metabolomics volatile organic compounds volatiles; |
| Notes: | "PubMed-not-MEDLINELammers, Alexander Lalk, Michael Garbeva, Paolina eng 398967434 - SFB/TRR261/Deutsche Forschungsgemeinschaft/ W10/2018/Wissenschaftsgemeinschaft Gottfried Wilhelm Leibniz e. V. via Leibniz WissenschaftsCampus - ComBioCat/ NNF16OC0021110/Novo Nordisk Foundation/ Review Switzerland 2022/01/22 Antibiotics (Basel). 2022 Jan 14; 11(1):109. doi: 10.3390/antibiotics11010109" |
