Title: | Fungal mating pheromones: choreographing the dating game |
Address: | "Graduate Program in Molecular Biology, Cellular Biology, and Biochemistry, Brown University, Providence, RI 02912, United States" |
DOI: | 10.1016/j.fgb.2011.04.001 |
ISSN/ISBN: | 1096-0937 (Electronic) 1087-1845 (Print) 1087-1845 (Linking) |
Abstract: | "Pheromones are ubiquitous from bacteria to mammals - a testament to their importance in regulating inter-cellular communication. In fungal species, they play a critical role in choreographing interactions between mating partners during the program of sexual reproduction. Here, we describe how fungal pheromones are synthesized, their interactions with G protein-coupled receptors, and the signals propagated by this interaction, using Saccharomyces cerevisiae as a reference point. Divergence from this model system is compared amongst the ascomycetes and basidiomycetes, which reveals the wealth of information that has been gleaned from studying pheromone-driven processes across a wide spectrum of the fungal kingdom" |
Keywords: | "Basidiomycota/genetics/physiology *Gene Expression Regulation, Fungal Pheromones/*metabolism Recombination, Genetic Saccharomyces cerevisiae/*genetics/growth & development/metabolism/*physiology *Signal Transduction;" |
Notes: | "MedlineJones, Stephen K Jr Bennett, Richard J eng AI081704/AI/NIAID NIH HHS/ T32 GM007601/GM/NIGMS NIH HHS/ R21 AI081560/AI/NIAID NIH HHS/ R01 AI081704-01A2/AI/NIAID NIH HHS/ AI081560/AI/NIAID NIH HHS/ R21 AI081560-01A2/AI/NIAID NIH HHS/ R01 AI081704/AI/NIAID NIH HHS/ Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Review 2011/04/19 Fungal Genet Biol. 2011 Jul; 48(7):668-76. doi: 10.1016/j.fgb.2011.04.001. Epub 2011 Apr 8" |