| Title: | Essential Oils Extracted from Organic Propolis Residues: An Exploratory Analysis of Their Antibacterial and Antioxidant Properties and Volatile Profile |
| Author(s): | Ikeda NY; Ambrosio CMS; Miano AC; Rosalen PL; Gloria EM; Alencar SM; |
| Address: | "Department of Agri-Food Industry, Food and Nutrition, 'Luiz de Queiroz' College of Agriculture, University of Sao Paulo, Piracicaba, Sao Paulo 13418-900, SP, Brazil. Direccion de Investigacion y Desarrollo, Universidad Privada del Norte (UPN), Trujillo 13011, Peru. Biological Sciences Graduate Program, Federal University of Alfenas-UNIFAL-MG, Rua Gabriel Monteiro da Silva, 700, Alfenas 37130-001, MG, Brazil. Department of Biosciences, Piracicaba Dental School, University of Campinas, Av. Limeira, 901, Piracicaba 13414-903, SP, Brazil. Department of Biological Science, 'Luiz de Queiroz' College of Agriculture, University of Sao Paulo, Piracicaba, Sao Paulo 13418-900, SP, Brazil" |
| DOI: | 10.3390/molecules26154694 |
| ISSN/ISBN: | 1420-3049 (Electronic) 1420-3049 (Linking) |
| Abstract: | "The industrial processing of crude propolis generates residues. Essential oils (EOs) from propolis residues could be a potential source of natural bioactive compounds to replace antibiotics and synthetic antioxidants in pig production. In this study, we determined the antibacterial/antioxidant activity of EOs from crude organic propolis (EOP) and from propolis residues, moist residue (EOMR), and dried residue (EODR), and further elucidated their chemical composition. The EOs were extracted by hydrodistillation, and their volatile profile was tentatively identified by GC-MS. All EOs had an antibacterial effect on Escherichia coli and Lactobacillus plantarum as they caused disturbances on the growth kinetics of both bacteria. However, EODR had more selective antibacterial activity, as it caused a higher reduction in the maximal culture density (D) of E. coli (86.7%) than L. plantarum (46.9%). EODR exhibited mild antioxidant activity, whereas EOMR showed the highest antioxidant activity (ABTS = 0.90 mumol TE/mg, FRAP = 463.97 mumol Fe(2+)/mg) and phenolic content (58.41 mg GAE/g). Each EO had a different chemical composition, but alpha-pinene and beta-pinene were the major compounds detected in the samples. Interestingly, specific minor compounds were detected in a higher relative amount in EOMR and EODR as compared to EOP. Therefore, these minor compounds are most likely responsible for the biological properties of EODR and EOMR. Collectively, our findings suggest that the EOs from propolis residues could be resourcefully used as natural antibacterial/antioxidant additives in pig production" |
| Keywords: | "*Anti-Bacterial Agents/chemistry/isolation & purification/pharmacology *Antioxidants/chemistry/isolation & purification/pharmacology Escherichia coli/*growth & development Lactobacillus plantarum/*growth & development *Oils, Volatile/chemistry/isolation &;" |
| Notes: | "MedlineIkeda, Natalia Y Ambrosio, Carmen M S Miano, Alberto Claudio Rosalen, Pedro L Gloria, Eduardo M Alencar, Severino M eng Switzerland 2021/08/08 Molecules. 2021 Aug 3; 26(15):4694. doi: 10.3390/molecules26154694" |
