Title: | HS-GC/MS method development and exposure assessment of volatile organic compounds from food packaging into food simulants |
Author(s): | Hwang JB; Lee S; Yeum J; Kim M; Choi JC; Park SJ; Kim J; |
Address: | "Food Additives and Packaging Division, National Institute of Food and Drug Safety Evaluation , Cheongju , Republic of Korea. Department of Chemistry, Chungnam National University , Daejeon , Republic of Korea" |
Journal Title: | Food Addit Contam Part A Chem Anal Control Expo Risk Assess |
DOI: | 10.1080/19440049.2019.1642520 |
ISSN/ISBN: | 1944-0057 (Electronic) 1944-0057 (Linking) |
Abstract: | "A simultaneous headspace-gas chromatography/mass spectrometry (HS-GC/MS) method was developed and validated to determine the migration of 12 volatile organic compounds (methanol, acetone, methylethylketone, ethylacetate, isopropylalcohol, benzene, toluene, ethylbenzene, xylene, cumene, propylbenzene, and styrene) from food contact materials into food simulants (water, 4% acetic acid, 50% ethanol, and n-heptane). The limits of detection and quantification were 0.007-0.201 mg L(-1) and 0.023-0.668 mg L(-1), respectively. The method was applied to 205 samples of paper/paperboard, polyethylene, polypropylene, polystyrene, and polyethylene terephthalate. The estimated daily intake (EDI) was calculated using the migration results. Exposure assessments were carried out to compare the EDI to the tolerable daily intake (TDI); the results indicated that the EDI of styrene represented only a small percentage (8.0%) of the TDI. This analytical method will be a useful tool to examine levels of various volatile compounds migrating from food packaging to food simulants using HS-GC/MS method" |
Keywords: | Acetic Acid/chemistry Ethanol/chemistry *Food Analysis Food Contamination/*analysis *Food Packaging Gas Chromatography-Mass Spectrometry Heptanes/chemistry Temperature Volatile Organic Compounds/*analysis Water/chemistry Volatile organic compound exposure; |
Notes: | "MedlineHwang, Joung Boon Lee, Subi Yeum, Jinhwa Kim, MeeKyung Choi, Jae Chun Park, Se-Jong Kim, Jeongkwon eng England 2019/07/31 Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2019 Oct; 36(10):1574-1583. doi: 10.1080/19440049.2019.1642520. Epub 2019 Jul 30" |