| Title: | Glomerular interactions in olfactory processing channels of the antennal lobes |
| Author(s): | Heinbockel T; Shields VD; Reisenman CE; |
| Address: | "Department of Anatomy, Howard University College of Medicine, 520 W St., N.W., Washington, DC, 20059, USA, theinbockel@howard.edu" |
| Journal Title: | J Comp Physiol A Neuroethol Sens Neural Behav Physiol |
| DOI: | 10.1007/s00359-013-0842-6 |
| ISSN/ISBN: | 1432-1351 (Electronic) 0340-7594 (Print) 0340-7594 (Linking) |
| Abstract: | "An open question in olfactory coding is the extent of interglomerular connectivity: do olfactory glomeruli and their neurons regulate the odorant responses of neurons innervating other glomeruli? In the olfactory system of the moth Manduca sexta, the response properties of different types of antennal olfactory receptor cells are known. Likewise, a subset of antennal lobe glomeruli has been functionally characterized and the olfactory tuning of their innervating neurons identified. This provides a unique opportunity to determine functional interactions between glomeruli of known input, specifically, (1) glomeruli processing plant odors and (2) glomeruli activated by antennal stimulation with pheromone components of conspecific females. Several studies describe reciprocal inhibitory effects between different types of pheromone-responsive projection neurons suggesting lateral inhibitory interactions between pheromone component-selective glomerular neural circuits. Furthermore, antennal lobe projection neurons that respond to host plant volatiles and innervate single, ordinary glomeruli are inhibited during antennal stimulation with the female's sex pheromone. The studies demonstrate the existence of lateral inhibitory effects in response to behaviorally significant odorant stimuli and irrespective of glomerular location in the antennal lobe. Inhibitory interactions are present within and between olfactory subsystems (pheromonal and non-pheromonal subsystems), potentially to enhance contrast and strengthen odorant discrimination" |
| Keywords: | Animals Arthropod Antennae/*anatomy & histology/physiology Insecta Nerve Net/*physiology Olfactory Pathways/*physiology Olfactory Receptor Neurons/*physiology Signal Transduction Smell/*physiology; |
| Notes: | "MedlineHeinbockel, Thomas Shields, Vonnie D C Reisenman, Carolina E eng R15 DC007609/DC/NIDCD NIH HHS/ DC-007609/DC/NIDCD NIH HHS/ S06 GM008016/GM/NIGMS NIH HHS/ DC-02751/DC/NIDCD NIH HHS/ G12 MD007597/MD/NIMHD NIH HHS/ GM-08016/GM/NIGMS NIH HHS/ MD-007597/MD/NIMHD NIH HHS/ AI-23253/AI/NIAID NIH HHS/ R01 DC002751/DC/NIDCD NIH HHS/ Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Review Germany 2013/07/31 J Comp Physiol A Neuroethol Sens Neural Behav Physiol. 2013 Nov; 199(11):929-46. doi: 10.1007/s00359-013-0842-6. Epub 2013 Jul 28" |
