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J Agric Food Chem

Title:		2-Aminoacetophenone Is the Main Volatile Phase I Skatole Metabolite in Pietrain x Baden-Wurttemberg Hybrid Type Boars
Author(s):		Gerlach C; Elsinghorst PW; Schmarr HG; Wust M;
Address:		"Department of Nutrition and Food Sciences, Bioanalytics, University of Bonn , Endenicher Allee 11-13, D-53115 Bonn, Germany. Pharmaceutical Institute, Pharmaceutical Chemistry I, University of Bonn , An der Immenburg 4, D-53121 Bonn, Germany. ELFI Analytik GbR, Massenhausener Strasse 18a, D-85375 Neufahrn, Germany. Dienstleistungszentrum Landlicher Raum (DLR) Rheinpfalz, Competence Centre for Wine Research , Breitenweg 71, D-67435 Neustadt an der Weinstrasse, Germany"
Journal Title:		J Agric Food Chem
Year:		2016
Volume:		20160129
Issue:		5
Page Number:		1158 - 1163
DOI:		10.1021/acs.jafc.5b05729
ISSN/ISBN:		1520-5118 (Electronic) 0021-8561 (Linking)
Abstract:		"Skatole metabolites have been considered as putative contributors to boar taint. Recently, 2-aminoacetophenone, a volatile phase I skatole metabolite, was identified in back fat samples from boars of Pietrain x Baden-Wurttemberg hybrid type. This paper addresses the question of the physiological origin of the observed 2-aminoacetophenone in these pigs. Microsomal fractions from nine boars were isolated, and formation of skatole metabolites was subsequently analyzed by stable-isotope dilution analysis (SIDA) using headspace solid-phase microextraction gas chromatography-mass spectrometry (HS-SPME/GC-MS). Significant breed-related differences in phase I skatole metabolism were observed, explaining the high levels of 2-aminoacetophenone in Pietrain x Baden-Wurttemberg hybrid type boars"
Keywords:		"Acetophenones/chemistry/*metabolism Animals Breeding Female Hybridization, Genetic Male Molecular Structure Skatole/chemistry/*metabolism Sus scrofa/genetics/*metabolism Swine Volatile Organic Compounds/*chemistry/metabolism Hs-spme/gc-ms Sida metabolism;"
Notes:		"MedlineGerlach, Christoph Elsinghorst, Paul W Schmarr, Hans-Georg Wust, Matthias eng Research Support, Non-U.S. Gov't 2016/01/26 J Agric Food Chem. 2016 Feb 10; 64(5):1158-63. doi: 10.1021/acs.jafc.5b05729. Epub 2016 Jan 29"