| Title: | "Shift in phagocytosis, lysosomal stability, lysozyme activity, apoptosis and cell cycle profile in the coelomocytes of earthworm of polluted soil near a tannery field of India" |
| Author(s): | Gautam A; Ray A; Manna S; Sarkar MP; Ghosh AR; Ray M; Ray S; |
| Address: | "Aquatic Toxicology Laboratory, Department of Zoology, University of Calcutta, 35 Ballygunge Circular Road, Kolkata, 700019, West Bengal, India. Electronic address: arunodaya.ecotox@gmail.com. Aquatic Toxicology Laboratory, Department of Zoology, University of Calcutta, 35 Ballygunge Circular Road, Kolkata, 700019, West Bengal, India. Electronic address: abhishekzooa05@gmail.com. Semiochemicals and Lipid Laboratory, Department of Life Science, Presidency University, 86/1, College Street, Kolkata, 700073, West Bengal, India. Electronic address: sourabhone.sourav@gmail.com. Semiochemicals and Lipid Laboratory, Department of Life Science, Presidency University, 86/1, College Street, Kolkata, 700073, West Bengal, India. Electronic address: mousumipsarkar1@gmail.com. Department of Environmental Science, The University of Burdwan, Golapbag, Bardhaman, 713104, West Bengal, India. Electronic address: mousumipsarkar1@gmail.com. Aquatic Toxicology Laboratory, Department of Zoology, University of Calcutta, 35 Ballygunge Circular Road, Kolkata, 700019, West Bengal, India. Electronic address: mitalirayin@yahoo.co.in. Aquatic Toxicology Laboratory, Department of Zoology, University of Calcutta, 35 Ballygunge Circular Road, Kolkata, 700019, West Bengal, India. Electronic address: raysnailmail@rediffmail.com" |
| DOI: | 10.1016/j.ecoenv.2020.110713 |
| ISSN/ISBN: | 1090-2414 (Electronic) 0147-6513 (Linking) |
| Abstract: | "Calcutta Leather Complex of the state of West Bengal, India has been designated as an industrially active zone with around 400 active tannery units. This area spanning 4.5?ª+km(2) is surrounded by human habitation. The soil of this region is contaminated with metal pollutants and exhibited an alteration in selected physicochemical parameters, namely cation exchange capacity, moisture content, pH, total nitrogen, total organic carbon and water holding capacity. Metaphire posthuma, a common variety of endogeic earthworm inhabiting this region is thus continuously exposed to these toxic metals. Coelomocytes, the chief immune effector cells of earthworm presented a shift in phagocytosis, lysosomal membrane stability, lysozyme and phosphatase activity, physiological apoptosis and cell cycle profile of M. posthuma sampled from the soil of tannery industry. Presence of high concentration of toxic metals and change in the physicochemical characteristics of soil led to a state of cellular stress and immunocompromisation in M. posthuma, a common inhabitant of soil of this region. Experimental endpoints bear ecotoxicological significance as biomarkers of physiological stress in earthworm for monitoring the health of soil around this tannery industrial zone" |
| Keywords: | Animals Apoptosis/drug effects Cell Cycle/drug effects Environmental Biomarkers Humans India Industry Lysosomes/drug effects Metals/*toxicity Muramidase/metabolism Oligochaeta/*drug effects/enzymology/immunology/metabolism Phagocytosis/drug effects Soil/c; |
| Notes: | "MedlineGautam, Arunodaya Ray, Abhishek Manna, Sourav Sarkar, Mousumi Poddar Ghosh, Apurba Ratan Ray, Mitali Ray, Sajal eng Netherlands 2020/05/29 Ecotoxicol Environ Saf. 2020 Sep 1; 200:110713. doi: 10.1016/j.ecoenv.2020.110713. Epub 2020 May 25" |
