| Title: | Ram sexual pheromone: first approach of chemical identification |
| Author(s): | Cohen-Tannoudji J; Einhorn J; Signoret JP; |
| Address: | "Inra Laboratoire de Comportement Animal, Nouzilly F-37380 France" |
| DOI: | 10.1016/0031-9384(94)90329-8 |
| ISSN/ISBN: | 0031-9384 (Print) 0031-9384 (Linking) |
| Abstract: | "A series of experiments has been designed with the aim of identifying the pheromone of the ram responsible for the primer effect--induction of a LH peak and ovulation--in anoestrous ewes. In a first experiment, the pheromonal activity of various sources was tested, extract of ram fleece and ante orbital gland secretion induced characteristic changes in LH secretion, whereas urine was ineffective. A second experimental series showed that an accurate separation of the ram's fleece extract in acid and neutral fractions resulted in each case in a complete loss of activity whereas both together were efficient, indicating that the pheromonal action involves several components. From GC-MS analysis of both fractions, and after comparison of male and female wool extract, semi-synthetic formulations were tested. The association of synthetic 1,2-hexadecanediol and 1,2-octadecanediol with the natural acid fraction was efficient in stimulating LH release in anoestrous ewes. As the most frequent linear fatty acids have been shown not to be necessary, a role of branched and oxygenated fatty acids has been hypothesised" |
| Keywords: | "Animals Female Gas Chromatography-Mass Spectrometry Luteinizing Hormone/blood Male Ovulation/physiology Sex Attractants/*chemistry/physiology Sexual Behavior, Animal/*physiology Sheep/*physiology Wool/chemistry;" |
| Notes: | "MedlineCohen-Tannoudji, J Einhorn, J Signoret, J P eng 1994/11/01 Physiol Behav. 1994 Nov; 56(5):955-61. doi: 10.1016/0031-9384(94)90329-8" |
