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Curr Biol

Title:		Systems biology: a switch for sex
Author(s):		Andrews SS; Arkin AP;
Address:		"Physical Biosciences Division, Lawrence Berkeley National Laboratory, 1 Cyclotron Road, M.S. 977-152, Berkeley, California 94720, USA. ssandrews@lbl.gov "
Journal Title:		Curr Biol
Year:		2007
Volume:		17
Issue:		11
Page Number:		R410 - R412
DOI:		10.1016/j.cub.2007.03.060
ISSN/ISBN:		0960-9822 (Print) 0960-9822 (Linking)
Abstract:		"The yeast pheromone response pathway works in a graded fashion, such that more pheromone leads to more response, but a recent study has shown that small modifications convert it into a bistable switch, with implications for the evolution and engineering of reaction networks"
Keywords:		"*Feedback, Physiological Gene Expression Regulation, Fungal Models, Biological Pheromones/*physiology Reproduction/physiology Saccharomyces cerevisiae/drug effects/*metabolism/physiology *Signal Transduction Systems Biology;"
Notes:		"MedlineAndrews, Steven S Arkin, Adam P eng Comment England 2007/06/07 Curr Biol. 2007 Jun 5; 17(11):R410-2. doi: 10.1016/j.cub.2007.03.060"