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Biosci Biotechnol Biochem

Title:		Genetic analysis of plasmid-specific pheromone signaling encoded by pPD1 in Enterococcus faecalis
Author(s):		Nakayama J; Suzuki A;
Address:		"Department of Applied Biological Chemistry, University of Tokyo, Japan"
Journal Title:		Biosci Biotechnol Biochem
Year:		1997
Volume:		61
Issue:		11
Page Number:		1796 - 1799
DOI:		10.1271/bbb.61.1796
ISSN/ISBN:		0916-8451 (Print) 0916-8451 (Linking)
Abstract:		"Certain plasmids in Enterococcus faecalis encode a mating response to recipient-produced peptide sex pheromones. Targeted disruption of tra genes on pPD1 suggested that TraA plays a central role in the plasmid-specific pheromone signaling pathway. TraA functioned as a negative regulator for the pheromone-inducible conjugal transfer. Complementation analysis of pPD1 tra gene mutants by pAD1 suggested that the pheromone binding function of TraC was non-specific between these plasmids, but the function of TraA and the pheromone shutdown function of TraB are plasmid-specific"
Keywords:		"Bacteriocins/*genetics Conjugation, Genetic/genetics/physiology Enterococcus faecalis/*genetics/*physiology Genes, Bacterial Genetic Complementation Test Plasmids/*genetics Sensitivity and Specificity Sex Attractants/*genetics/*physiology Signal Transduct;"
Notes:		"MedlineNakayama, J Suzuki, A eng Research Support, Non-U.S. Gov't England 1997/12/24 Biosci Biotechnol Biochem. 1997 Nov; 61(11):1796-9. doi: 10.1271/bbb.61.1796"