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Ann Trop Med Parasitol

Title:		Comparison of the sex-pheromone components of Lutzomyia longipalpis (Diptera:Psychodidae) from areas of visceral and atypical cutaneous leishmaniasis in Honduras and Cost Rica
Author(s):		Hamilton JG; Ward RD; Dougherty MJ; Maignon R; Ponce C; Ponce E; Noyes H; Zeledon R;
Address:		"Department of Biological Sciences, University of Keele, U.K"
Journal Title:		Ann Trop Med Parasitol
Year:		1996
Volume:		90
Issue:		5
Page Number:		533 - 541
DOI:		10.1080/00034983.1996.11813079
ISSN/ISBN:		0003-4983 (Print) 0003-4983 (Linking)
Abstract:		"The terpene components of extracts prepared from male Lutzomyia longipalpis (Diptera: Psychodidae) collected from four sites in Honduras and one in Costa Rica were analysed by high-performance liquid chromatography, gas chromatography and coupled gas chromatography--mass spectrometry. The terpene components of Lu. longipalpis from other regions of South America have previously been shown to be sex pheromones. The flies from the four areas of Honduras, where Leishmania chagasi infection may lead to visceral or atypical cutaneous leishmaniasis, were found to be homogenous, all producing 9-methylgermacrene-B. Three types of terpene (9-methylgermacrene-B, a novel homosesquiterpene and a small amount of diterpene) were detected in pools of flies from Liberia, Costa Rica, where only atypical cutaneous leishmaniasis has been found. These results indicate that there are probably at least two and possibly three distinct populations of Lu. longipalpis in this region. The clinical manifestation of Leishmania chagasi infection does not appear to be dependent on which population of Lu. longipalpis transmitted the parasite"
Keywords:		"Animals Chromatography, Gas Chromatography, High Pressure Liquid Costa Rica Gas Chromatography-Mass Spectrometry Honduras Insect Vectors Leishmaniasis, Cutaneous/transmission Leishmaniasis, Visceral/transmission Male Psychodidae/*chemistry Sesquiterpenes/;"
Notes:		"MedlineHamilton, J G Ward, R D Dougherty, M J Maignon, R Ponce, C Ponce, E Noyes, H Zeledon, R eng Wellcome Trust/United Kingdom Comparative Study Research Support, Non-U.S. Gov't England 1996/10/01 Ann Trop Med Parasitol. 1996 Oct; 90(5):533-41. doi: 10.1080/00034983.1996.11813079"