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Molecules

Title:		"Chamomile: A Review of Its Traditional Uses, Chemical Constituents, Pharmacological Activities and Quality Control Studies"
Author(s):		Dai YL; Li Y; Wang Q; Niu FJ; Li KW; Wang YY; Wang J; Zhou CZ; Gao LN;
Address:		"College of Pharmacy, Shandong University of Traditional Chinese Medicine, Ji'nan 250355, China"
Journal Title:		Molecules
Year:		2022
Volume:		20221223
Issue:		1
Page Number:		-
DOI:		10.3390/molecules28010133
ISSN/ISBN:		1420-3049 (Electronic) 1420-3049 (Linking)
Abstract:		"Matricaria chamomilla L. (MC) and Chamaemelum nobile (L.) All. (CN) are two varieties of Chamomile. These herbs have been used for thousands of years in Greece, Rome and ancient Egypt. Chamomile has been used for the treatment of stomach problems, cramps, dermatitis, and minor infections. The purpose of this study was to introduce the botanical characteristics and geographical distribution, traditional uses, chemical constituents, pharmacological activities, toxicity studies and quality control studies, and lay a theoretical foundation for the rational development and utilization of chamomile. This review powered that chemical constituents include flavonoids, coumarins, volatile oils, terpenes, organic acids, polysaccharides, and others. These compounds possess anticancer, anti-infective, anti-inflammatory, antithrombotic, antioxidant, hypolipidaemic, hypoglycaemic, antihypertensive, antidepressant, neuroprotective activities, among others. Chamomile is a widely used herb in traditional medicine. It brings great economic value due to its numerous pharmacological effects and traditional uses. However, more toxicity tests should be carried out to confirm its safety. There is need for further research to provide concrete scientific evidence and validate its medicinal properties"
Keywords:		"*Chamomile Plant Extracts/chemistry *Oils, Volatile/pharmacology/chemistry Terpenes Quality Control Medicine, Traditional Chamaemelum nobile (L.) all.Matricaria chamomilia L.chamomile chemical constituents pharmacological activities;"
Notes:		"MedlineDai, Yun-Lei Li, Ying Wang, Qi Niu, Feng-Jv Li, Kun-Wei Wang, Yun-Yu Wang, Jian Zhou, Chang-Zheng Gao, Li-Na eng Review Switzerland 2023/01/09 Molecules. 2022 Dec 23; 28(1):133. doi: 10.3390/molecules28010133"