Title: | "Separation, quantification and identification of non-volatile organic acids in body fluids by gas chromatography" |
Address: | "Faculty of General Medicine of the Charles' University, Diagnostic Centre for Congenital Metabolic Disorders, 121 11 Praha 2, Karlovo nam. 32, Czechoslovakia" |
DOI: | 10.1016/0731-7085(88)80040-2 |
ISSN/ISBN: | 0731-7085 (Print) 0731-7085 (Linking) |
Abstract: | "The present paper concentrates on the analysis of non-volatile organic acids in physiological fluids. The solvent extraction and DEAE-Sephadex extraction of organic acids, respectively, seem to be the most widely used methods for isolation of this group of compounds from the biological matrix. Gas chromatography-mass spectrometry (GC/MS) is the preferred method for the separation, quantification and identification. In three tables organic acids are divided into the classes according to a functional group, a survey of alkylation methods is given and retention indices of common urinary organic acids on various GC columns are summarized" |
Notes: | "PubMed-not-MEDLINEVerner, P eng England 1988/01/01 J Pharm Biomed Anal. 1988; 6(2):131-50. doi: 10.1016/0731-7085(88)80040-2" |