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« Previous Abstract[Research on hepatic steatosis during poisoning by volatile organic compounds. IV. Biochemical and histochemical studies of fatty livers induced by trichloroethylene poisoning]    Next Abstract"Ultrastructure of the foveal glands of the ticks, Dermacentor andersoni Stiles and D. variabilis (Say)" »

J Pharm Biomed Anal


Title:"Separation, quantification and identification of non-volatile organic acids in body fluids by gas chromatography"
Author(s):Verner P;
Address:"Faculty of General Medicine of the Charles' University, Diagnostic Centre for Congenital Metabolic Disorders, 121 11 Praha 2, Karlovo nam. 32, Czechoslovakia"
Journal Title:J Pharm Biomed Anal
Year:1988
Volume:6
Issue:2
Page Number:131 - 150
DOI: 10.1016/0731-7085(88)80040-2
ISSN/ISBN:0731-7085 (Print) 0731-7085 (Linking)
Abstract:"The present paper concentrates on the analysis of non-volatile organic acids in physiological fluids. The solvent extraction and DEAE-Sephadex extraction of organic acids, respectively, seem to be the most widely used methods for isolation of this group of compounds from the biological matrix. Gas chromatography-mass spectrometry (GC/MS) is the preferred method for the separation, quantification and identification. In three tables organic acids are divided into the classes according to a functional group, a survey of alkylation methods is given and retention indices of common urinary organic acids on various GC columns are summarized"
Keywords:
Notes:"PubMed-not-MEDLINEVerner, P eng England 1988/01/01 J Pharm Biomed Anal. 1988; 6(2):131-50. doi: 10.1016/0731-7085(88)80040-2"

 
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