| Title: | Phytochemical Analysis and Biological Activity of Three Stachys Species (Lamiaceae) from Romania |
| Author(s): | Stegarus DI; Lengyel E; Apostolescu GF; Botoran OR; Tanase C; |
| Address: | "National Research and Development Institute for Cryogenics and Isotopic Technologies-ICSI Ramnicu Valcea, 4th Uzinei Street, 240050 Ramnicu Valcea, Romania. Department of Agricultural Sciences and Food Engineering, Lucian Blaga University of Sibiu, Doctor Ion Ratiu 7, 550012 Sibiu, Romania. Department of Pharmacognosy & Phytotherapy, Faculty of Pharmacy, University of Medicine and Pharmacy of Craiova, 2 Petru Rares Street, 200349 Craiova, Romania. Department of Pharmaceutical Botany, 'George Emil Palade' University of Medicine, Pharmacy, Sciences and Technology of Targu Mures, 38 Gheorghe Marinescu Street, Targu Mures, 540139 Mures, Romania" |
| ISSN/ISBN: | 2223-7747 (Print) 2223-7747 (Electronic) 2223-7747 (Linking) |
| Abstract: | "Three species of Stachys genus (S. byzantina, S. officinalis, S. sylvatica) were investigated in the present study in terms of aromatic profile and total polyphenol content, as well as antibacterial activity and antioxidant capacity. Gas chromatography coupled with flame ionization detection (GC/FID) was used for exploration of the herbal alcoholic extracts. Using statistical analysis, volatile organic compounds (VOCs) and total phenolic chemical fingerprints were compared in order to describe differences and identify putative signature traits of the three Stachys species. The results showed that the analyzed Stachys extracts have a total polyphenol content being between 197 +/- 0.27 mg GAE/g for S. sylvatica and 232 +/- 43 mg GAE/g for S. officinalis. The antioxidant activity was between 444 +/- 58 mM Trolox/g (S. sylvatica) and 602 +/- 75 mM Trolox/g (S. officinalis). The volatile compounds identified were mostly sesquiterpenes, followed by monoterpenes and secondary compounds. The most abundant in all three species was germacrene D (21.9% 28-25.2%). The multivariate analysis demonstrated the potential of using plant tissue VOC profiles to discriminate between different Stachy species, with a total of 31 VOCs being identified from all three species. Although there were strong similarities among the three species' VOC profiles, distinctions can be made using chemometric analysis. The microbiological results showed an antimicrobial capacity of all three extracts, especially on Gram-positive bacteria. In addition to increasing consumers' understanding regarding the health benefits of these Stachy species, this investigation contributes to defining and preserving a precious genetic and cultural-historical biodiversity" |
| Keywords: | S.byzantina S.officinalis S.sylvatica antibacterial activity antioxidant activity polyphenols volatile compounds; |
| Notes: | "PubMed-not-MEDLINEStegarus, Diana Ionela Lengyel, Ecaterina Apostolescu, George Florian Botoran, Oana Romina Tanase, Corneliu eng Switzerland 2021/12/29 Plants (Basel). 2021 Dec 9; 10(12):2710. doi: 10.3390/plants10122710" |
