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Curr Genet


Title:"PkpA, a novel Phycomyces blakesleeanus serine/threonine protein kinase"
Author(s):Ruiz-Perez VL; Murillo FJ; Torres-Martinez S;
Address:"Departamento de Genetica y Microbiologia, Facultad de Biologia, Universidad de Murcia, Spain"
Journal Title:Curr Genet
Year:1995
Volume:28
Issue:4
Page Number:309 - 316
DOI: 10.1007/BF00326428
ISSN/ISBN:0172-8083 (Print) 0172-8083 (Linking)
Abstract:"This work reports the cloning and sequencing of pkpA, a gene of the filamentous fungus Phycomyces blakesleeanus, whose expression seems to be coupled to vegetative growth. This gene encodes a putative serine/threonine-specific protein kinase, whose sequence is related to that of the yeast protein STE20, involved in pheromone-response pathways, and to a number of MAPK kinase proteins. However, detailed analysis of the kinase sequence suggests that PkpA is a novel serine/threonine protein kinase that probably participates as an intermediate in an intracellular system controlling nuclear proliferation in P. blakesleeanus"
Keywords:"Amino Acid Sequence Base Sequence Binding Sites Cell Division Cloning, Molecular Conserved Sequence/genetics DNA Primers Fungal Proteins/chemistry Gene Expression Regulation, Fungal Genes, Fungal Introns/genetics Molecular Sequence Data Phycomyces/enzymol;"
Notes:"MedlineRuiz-Perez, V L Murillo, F J Torres-Martinez, S eng Research Support, Non-U.S. Gov't 1995/09/01 Curr Genet. 1995 Sep; 28(4):309-16. doi: 10.1007/BF00326428"

 
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