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Nat Prod Res

Title:		"Volatile composition, antibacterial and antioxidant activities of artemisia tournefortiana Reichb. from Kashmir, India"
Author(s):		Qadir M; Maurya AK; Agnihotri VK; Shah WA;
Address:		"Department of Chemistry, University of Kashmir, Srinagar, Jammu and Kashmir, India. Natural Product Chemistry and Process Development Division, CSIR-Institute of Himalayan Bioresource Technology, Palampur, Himachal Pradesh, India"
Journal Title:		Nat Prod Res
Year:		2021
Volume:		20190528
Issue:		1
Page Number:		152 - 156
DOI:		10.1080/14786419.2019.1613990
ISSN/ISBN:		1478-6427 (Electronic) 1478-6419 (Linking)
Abstract:		"The importance of the present study is to find out the phytochemical profile of essential oil (EO) of Artemisia tournefortiana Reichb. and its biological evaluation. Nineteen volatile constituents were identified from EO representing 93.47% of total oil composition. Oxygenated monoterpenes (54.46%) were found to be dominant over other class of compounds. cis-spiroether (47.66%), Z-beta-farnesene (22.83%), trans-nerolidol (3.89%) and camphor (3.80%) were found to be the major constituents. cis-spiroether is first time identified in this region. Antibacterial effects were observed against both gram-positive and gram-negative bacteria with maximum zone of inhibition (32 mm) against Staphylococcus aureus and minimum inhibitory concentration (MIC) of all tested strains were found in the range of 1.6-3.4 microg/mL. Hence the antimicrobial effect of this plant EO obtained from the natural source could be utilised in order to overcome the problem of microbial drug resistance. The EO showed moderate antioxidant effect through DPPH assay with IC(50) value of 56.2 microg/mL. The significant antioxidant activity can be attributed to the presence of various conjugated secondary metabolites, phenolics and hydroxyl group bearing constituents present in the essential oil.[Figure: see text]"
Keywords:		"Anti-Bacterial Agents/chemistry/*pharmacology Antioxidants/chemistry/*pharmacology Artemisia/*chemistry/metabolism Camphor/analysis Drug Evaluation, Preclinical Gas Chromatography-Mass Spectrometry Gram-Negative Bacteria/drug effects Gram-Positive Bacteri;"
Notes:		"MedlineQadir, Mahpara Maurya, Antim Kumar Agnihotri, Vijai Kant Shah, Wajaht A eng England 2019/05/29 Nat Prod Res. 2021 Jan; 35(1):152-156. doi: 10.1080/14786419.2019.1613990. Epub 2019 May 28"