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Food Chem

Title:		Understanding retention and metabolization of aroma compounds using an in vitro model of oral mucosa
Author(s):		Ployon S; Brule M; Andriot I; Morzel M; Canon F;
Address:		"Centre des Sciences du Gout et de l'Alimentation, AgroSup Dijon, CNRS, INRAE, Universite de Bourgogne Franche-Comte, Dijon F-21000, France. Centre des Sciences du Gout et de l'Alimentation, AgroSup Dijon, CNRS, INRAE, Universite de Bourgogne Franche-Comte, Dijon F-21000, France; ChemoSens Platform, CSGA, Dijon F-21000, France. Centre des Sciences du Gout et de l'Alimentation, AgroSup Dijon, CNRS, INRAE, Universite de Bourgogne Franche-Comte, Dijon F-21000, France. Electronic address: francis.canon@inrae.fr"
Journal Title:		Food Chem
Year:		2020
Volume:		20200222
Issue:
Page Number:		126468 -
DOI:		10.1016/j.foodchem.2020.126468
ISSN/ISBN:		1873-7072 (Electronic) 0308-8146 (Linking)
Abstract:		"The mechanism leading to aroma persistence during eating is not fully described. This study aims at better understanding the role of the oral mucosa in this phenomenon. Release of 14 volatile compounds from different chemical classes was studied after exposure to in vitro models of oral mucosa, at equilibrium by Gas-Chromatography-Flame Ionization Detection (GC-FID) and in dynamic conditions by Proton Transfer Reaction- Mass Spectrometry (PTR-MS). Measurements at equilibrium showed that mucosal hydration reduced the release of only two compounds, pentan-2-one and linalool (p < 0.05), and suggested that cells could metabolize aroma compounds from different chemical families (penta-2,3-dione, trans-2-hexen-1-al, ethyl hexanoate, nonan- and decan-2-one). Dynamic analyses for pentan-2-one and octan-2-one evidenced that the constituents of the mucosal pellicle influenced release kinetics differently depending on molecule hydrophobicity. This work suggests that mucosal cells can metabolize aroma compounds and that non-covalent interactions occur between aroma compounds and oral mucosa depending on aroma chemical structure"
Keywords:		Acyclic Monoterpenes/analysis/metabolism Eating Gas Chromatography-Mass Spectrometry Humans Mouth Mucosa/*drug effects/*metabolism *Odorants/analysis Pentanones/analysis/metabolism Saliva Volatile Organic Compounds/*analysis Aroma metabolism Aroma persist;
Notes:		"MedlinePloyon, Sarah Brule, Marine Andriot, Isabelle Morzel, Martine Canon, Francis eng England 2020/03/04 Food Chem. 2020 Jul 15; 318:126468. doi: 10.1016/j.foodchem.2020.126468. Epub 2020 Feb 22"