| Title: | Geoherbalism evaluation of Radix Angelica sinensis based on electronic nose |
| Address: | "Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100193, China. Electronic address: zshzha@gmail.com. Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100193, China; Guang' anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, China. Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100193, China. Electronic address: lfhuang@implad.ac.cn" |
| DOI: | 10.1016/j.jpba.2014.10.033 |
| ISSN/ISBN: | 1873-264X (Electronic) 0731-7085 (Linking) |
| Abstract: | "Radix Angelica sinensis (Danggui, DG), derived from the dry root of Angelicae sinensis, is popularly used for its antioxidant, hematinic and immuno-enhancement. However, DG from different origins possess different quality, and difficult to identity. In this study, we used electronic nose technique to investigate DG from different producing areas for monitoring the correlation of origin and quality. The electronic nose was employed to establish classification model of DG originated from four main producing areas of Gansu, Yunnan, Sichuan and Hubei in China. Principal component analysis (PCA) and discriminant function analysis (DFA) were performed to differentiate DG samples from four main producing areas. The content of phthalides of DG were determined to confirm the quality changes and investigate its correlation with the odor response values by Gas Chromatography-Mass Spectrometer (GC-MS). The results of PCA and DFA analysis showed that the electronic nose could accurately distinguish DG from four main producing areas. The method of electronic nose for identification could be verified by GC-MS technology, and the main ingredient content was consistent with its odor of DG. In conclusion, electronic nose could effectively identify different origins of DG, and could be applied for rapid identification and quality control of genuine Angelica herbs" |
| Keywords: | "Angelica sinensis/*chemistry/growth & development China Drugs, Chinese Herbal/*analysis/isolation & purification *Electronic Nose Gas Chromatography-Mass Spectrometry Geography, Medical Plant Roots/chemistry Principal Component Analysis Species Specificit;" |
| Notes: | "MedlineZheng, Sihao Ren, Weiguang Huang, Linfang eng Research Support, Non-U.S. Gov't England 2014/12/30 J Pharm Biomed Anal. 2015 Feb; 105:101-106. doi: 10.1016/j.jpba.2014.10.033. Epub 2014 Dec 5" |
