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Commun Integr Biol

Title:		Zebrafish olfactory receptor ORA1 recognizes a putative reproductive pheromone
Author(s):		Ahuja G; Korsching S;
Address:		"Institute for Genetics; University at Cologne ; Cologne, Germany"
Journal Title:		Commun Integr Biol
Year:		2014
Volume:		20141111
Issue:		5
Page Number:		-
DOI:		10.4161/19420889.2014.970501
ISSN/ISBN:		1942-0889 (Print) 1942-0889 (Electronic) 1942-0889 (Linking)
Abstract:		"Teleost v1r-related ora genes constitute a small and highly conserved olfactory receptor gene family, and their direct orthologs are present in lineages as distant as cartilaginous fishes. Recently, the first member of the ora gene family was deorphanized. ORA1 detects p-hydroxyphenylacetic acid with high sensitivity and specificity. This compound elicits olfactory-mediated oviposition behavior in adult zebrafish mating pairs, suggesting a potential function as a reproductive pheromone for pHPAA itself or a related substance. This association of an odor and its cognate receptor with an oviposition response may provide a molecular basis for studying neural circuits involved in fish reproduction"
Keywords:		V1R-like calcium imaging heterologous expression oviposition pheromone tyrosine zebrafish;
Notes:		"PubMed-not-MEDLINEAhuja, Gaurav Korsching, Sigrun eng 2014/10/01 Commun Integr Biol. 2014 Nov 11; 7(5):e970501. doi: 10.4161/19420889.2014.970501. eCollection 2014 Oct"