« Previous AbstractEvolving protein functional diversity in new genes of Drosophila    Next AbstractApplication of dynamic liquid-phase microextraction and injection port derivatization combined with gas chromatography-mass spectrometry to the determination of acidic pharmaceutically active compounds in water samples »

Anal Chem

Title:		Headspace water-based liquid-phase microextraction
Author(s):		Zhang J; Su T; Lee HK;
Address:		"Department of Chemistry, National University of Singapore, 3 Science Drive 3, Republic of Singapore 117543"
Journal Title:		Anal Chem
Year:		2005
Volume:		77
Issue:		7
Page Number:		1988 - 1992
DOI:		10.1021/ac040129h
ISSN/ISBN:		0003-2700 (Print) 0003-2700 (Linking)
Abstract:		"A new organic-free mode of headspace liquid-phase microextraction termed headspace water-based liquid-phase microextraction has been developed. Five phenols were used as model compounds in the development and evaluation of the procedure. Parameters affecting the extraction efficiency were investigated. Under optimal extraction conditions, very high enrichment factors were achieved. Since only water (with sodium hydroxide to adjust the pH) and a conventional microsyringe were used, this new technique is affordable, efficient, and convenient for extraction of volatile and semivolatile ionizable compounds. In addition, in combination with capillary electrophoresis, the entire analytical process is totally organic solvent-free and is thus environmentally friendly"
Keywords:		"Chemistry Techniques, Analytical/instrumentation/*methods Electrophoresis, Capillary Hydrogen-Ion Concentration Phenols/analysis/*isolation & purification Sodium Hydroxide/chemistry Temperature Water/analysis;"
Notes:		"MedlineZhang, Jie Su, Tao Lee, Hian Kee eng Research Support, Non-U.S. Gov't 2005/04/02 Anal Chem. 2005 Apr 1; 77(7):1988-92. doi: 10.1021/ac040129h"