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Cell Biol Int

Title:		Does yeast shmooing mean a commitment to apoptosis?
Author(s):		Zadrag R; Wojnar L; Bartosz G; Bilinski T;
Address:		"Department of Biochemistry and Cell Biology, University of Rzeszow, ul. Rejtana 16C, 35-959 Rzeszow, Poland"
Journal Title:		Cell Biol Int
Year:		2006
Volume:		20051222
Issue:		3
Page Number:		205 - 209
DOI:		10.1016/j.cellbi.2005.10.023
ISSN/ISBN:		1065-6995 (Print) 1065-6995 (Linking)
Abstract:		"Treatment of yeast Saccharomyces cerevisiae with alpha-pheromone has been reported to lead to massive apoptosis of cells finding no conjugation partner [Severin FF, Hyman AA. Pheromone induces programmed cell death in S. cerevisiae. Curr Biol 2002;12:R233-5]. We report here that this effect is not common in yeast. Using different yeast strains, we demonstrate that identical treatment results in a low mortality even after prolonged treatment with the pheromone. These findings are followed by a general discussion of the biological relevance of apoptosis in yeast"
Keywords:		Apoptosis/*drug effects Mating Factor Peptides/*pharmacology Reactive Oxygen Species/metabolism Time Factors Yeasts/*cytology/*drug effects/physiology;
Notes:		"MedlineZadrag, Renata Wojnar, Leszek Bartosz, Grzegorz Bilinski, Tomasz eng Research Support, Non-U.S. Gov't England 2005/12/27 Cell Biol Int. 2006 Mar; 30(3):205-9. doi: 10.1016/j.cellbi.2005.10.023. Epub 2005 Dec 22"