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Acta Crystallogr D Struct Biol

Title:		The actions of volatile anesthetics: a new perspective
Author(s):		Weinrich M; Worcester DL;
Address:		"NIST Center for Neutron Research, Gaithersburg, MD 20899, USA"
Journal Title:		Acta Crystallogr D Struct Biol
Year:		2018
Volume:		20181130
Issue:		Pt 12
Page Number:		1169 - 1177
DOI:		10.1107/S2059798318004771
ISSN/ISBN:		2059-7983 (Electronic) 2059-7983 (Linking)
Abstract:		"This article reviews recent work in applying neutron and X-ray scattering towards the elucidation of the molecular mechanisms of volatile anesthetics. Experimental results on domain mixing in ternary lipid mixtures, and the influence of volatile anesthetics and hydrostatic pressure are placed in the contexts of ion-channel function and receptor trafficking at the postsynaptic density"
Keywords:		Anesthetics/*pharmacology Animals Humans Hydrostatic Pressure Ion Channels/chemistry/metabolism Membrane Lipids/chemistry/*metabolism Membrane Microdomains/chemistry/drug effects/metabolism Membrane Proteins/chemistry/*metabolism Neuronal Plasticity/drug;
Notes:		"MedlineWeinrich, Michael Worcester, David L eng Review 2019/01/04 Acta Crystallogr D Struct Biol. 2018 Dec 1; 74(Pt 12):1169-1177. doi: 10.1107/S2059798318004771. Epub 2018 Nov 30"