| Title: | Deconstructing pheromone-mediated behavior one layer at a time |
| Author(s): | Sanchez-Andrade G; Logan DW; |
| Address: | "Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK. dl5@sanger.ac.uk" |
| ISSN/ISBN: | 1741-7007 (Electronic) 1741-7007 (Linking) |
| Abstract: | "The vomeronasal organ, a sensory structure within the nasal cavity of most tetrapods, detects pheromones that influence socio-sexual behavior. It has two neuronal layers, each patterned by distinct receptor sub-families coupled to different G-proteins. Work recently published in this journal found female mice with one layer genetically inactivated are deficient in a surprisingly wide range of reproductive behaviors, providing new insights into how the nose can influence the brain" |
| Keywords: | "Animals Female GTP-Binding Proteins/*metabolism Male Pheromones/*pharmacology Reproduction/*drug effects Sexual Behavior, Animal/*drug effects;" |
| Notes: | "MedlineSanchez-Andrade, Gabriela Logan, Darren W eng Comment England 2014/06/03 BMC Biol. 2014 May 29; 12:33. doi: 10.1186/1741-7007-12-33" |
