| Title: | Antioxidant and enzyme-inhibitory activity of peppermint extracts and essential oils obtained by conventional and emerging extraction techniques |
| Author(s): | Pavlic B; Teslic N; Zengin G; Durovic S; Rakic D; Cvetanovic A; Gunes AK; Zekovic Z; |
| Address: | "University of Novi Sad, Faculty of Technology, Blvd. cara Lazara 1, 21000 Novi Sad, Serbia. University of Novi Sad, Institute of Food Technology, Blvd. cara Lazara 1, 21000 Novi Sad, Serbia. Department of Biology, Science Faculty, Selcuk Unviersity, Campus, Konya 42130, Turkey. University of Belgrade, Institute of General and Physical Chemistry, Studentski trg 12/V, 11158 Belgrade, Serbia. University of Novi Sad, Faculty of Technology, Blvd. cara Lazara 1, 21000 Novi Sad, Serbia. Electronic address: zzekovic@tf.uns.ac.rs" |
| DOI: | 10.1016/j.foodchem.2020.127724 |
| ISSN/ISBN: | 1873-7072 (Electronic) 0308-8146 (Linking) |
| Abstract: | "Peppermint is widely used medicinal plant with distinguished bioactive potential, therefore, the aim of present work was to develop novel peppermint extracts with high activity by application of traditional and emerging separation techniques. Conventional hydrodistillation and microwave-assisted hydrodistillation (MWHD) were applied for recovery of essential oil (EO), while organic solvent extraction using Soxhlet apparatus, microwave-assisted and ultrasound-assisted process and supercritical fluid extraction (SFE) were applied for non-selective recovery of peppermint lipophilic extracts. Extracts were characterized in terms of terpenoids profile with special emphasis on content of major compounds (mentol, menthone, isomenthol and eucalyptol). Antioxidant activity (DPPH, ABTS, CUPRAC, FRAP, chelating and phosphomolybdenum assay) and enzyme-inhibitory assays (acetylcholinesterase, butyrylcholinesterase, tyrosinase, amylase and glucosidase inhibition) were used for screening of peppermint bioactivity. MWHD was recognized as alternative for traditional process in EO recovery, while SFE extracts were useful for green production of solvent-free peppermint extracts rich in terpenoids and other lipophilic bioactives" |
| Keywords: | "Acetylcholinesterase/chemistry/metabolism Antioxidants/*chemistry Chromatography, Supercritical Fluid Enzyme Inhibitors/*chemistry/metabolism Mentha piperita/*chemistry/metabolism Microwaves Oils, Volatile/*chemistry Plant Extracts/*chemistry Polyphenols/;" |
| Notes: | "MedlinePavlic, Branimir Teslic, Nemanja Zengin, Gokhan Durovic, Sasa Rakic, Dusan Cvetanovic, Aleksandra Gunes, A K Zekovic, Zoran eng England 2020/08/17 Food Chem. 2021 Feb 15; 338:127724. doi: 10.1016/j.foodchem.2020.127724. Epub 2020 Aug 2" |
