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Clin Ter

Title:		Dogs'olfactory diagnostics applied on human species: state of the art and clinical perspectives
Author(s):		Palmieri B; Nardo B; Lippi G; Palmieri L; Vadala M; Laurino C;
Address:		"Dipartimento Chirurgico, Medico, Odontoiatrico e di Scienze Morfologiche con Interesse Trapiantologico, Oncologico e di Medicina Rigenerativa, Universita degli Studi di Modena e Reggio Emilia, Modena - Associazione Italiana per la Ricerca sulle Malattie Oncologiche (AIRMO), Milano. Dipartimento di Scienze Mediche e Chirurgiche, Universita degli Studi di Bologna, Bologna. Sezione di Biochimica Clinica, Universita degli Studi di Verona, Verona, Italia. Dipartimento Chirurgico, Medico, Odontoiatrico e di Scienze Morfologiche con Interesse Trapiantologico, Oncologico e di Medicina Rigenerativa, Universita degli Studi di Modena e Reggio Emilia, Modena"
Journal Title:		Clin Ter
Year:		2016
Volume:		167
Issue:		4
Page Number:		e78 - e84
DOI:		10.7417/CT.2016.1943
ISSN/ISBN:		1972-6007 (Electronic) 0009-9074 (Linking)
Abstract:		"Dogs'smell ability is about 10000-100000 more developed than humans' one. Dogs smell is usually exploited in forensic medicine, to find missing people and specific substances showing peculiar sensorial features. In clinic, there is the possibility to take advantage of dogs smell, which are conveniently trained, for the screening of cancers and other diseases. The common feature is the presence of molecules in organic samples that may be considered as biomarkers of a specific pathology. In cancer, scientific evidences exist about screening of melanoma, lung, breast, rectum, ovarian, prostate and bladder cancer. Instead, other pathologies manifest the presence of organic volatile compounds in biologic materials, such as spit, faeces and urine that may be studied by dogs smell in order to identify the presence of a specific disease. This review shows the state of the art of actual dogs' olfactory ability based on scientific principles and the advantages and the disadvantages of this method. The authors also reveal some potential pathologies joined by the presence of organic volatile compounds, which may be investigated by dogs smell"
Keywords:		Animals Biomarkers *Diagnostic Techniques and Procedures Dogs Humans Male Neoplasms/*diagnosis Olfactory Bulb/*physiology Olfactory Pathways/*physiology Sensitivity and Specificity Smell/*physiology Volatile Organic Compounds Cancer Diagnosis Diseases Org;
Notes:		"MedlinePalmieri, B Nardo, B Lippi, G Palmieri, L Vadala, M Laurino, C eng Review Italy 2016/09/07 Clin Ter. 2016 Jul-Aug; 167(4):e78-84. doi: 10.7417/CT.2016.1943"