| Title: | Methyl-testosterone induces male-typical ventilatory behavior in response to putative steroidal pheromones in female round gobies (Neogobius melanostomus) |
| Address: | "Department of Biological Sciences, University of Alberta, Edmonton, Alberta, Canada T6G 2E9. cmurph4@lsu.edu" |
| ISSN/ISBN: | 0018-506X (Print) 0018-506X (Linking) |
| Abstract: | "Male round gobies (Neogobius melanostomus) transiently increase their rate of ventilation when exposed to nanomolar concentrations of three putative steroidal pheromones (etiocholanolone, ETIO; estrone, E1; estradiol-glucuronide, E2-3g), whereas females exhibit this response only to ETIO. In this study we implanted females with Silastic capsules that were empty (Blank) or filled with methyl-testosterone (MT) to determine whether androgen induces a male-typical pattern of ventilatory response. As with untreated females in our previous studies, Blank females increased ventilation only in response to ETIO. In contrast, MT females tested 2-3 weeks postimplant responded not only to ETIO, but also to E1 and E2-3g. These results provide the first demonstration of an androgen inducing a male-typical behavioral response to a steroidal pheromone in adult female fish. Together with our previous findings of sexually isomorphic sensory responses to steroid odorants, the present results also suggest that a central action of androgen is responsible for sexually dimorphic behavioral responses to putative pheromonal steroids in Neogobius" |
| Keywords: | "Animals Drug Implants Female Male Methyltestosterone/administration & dosage/*pharmacology Pheromones/*physiology Respiration/*drug effects *Respiratory Physiological Phenomena *Sex Characteristics Sexual Behavior, Animal/*drug effects/*physiology Testost;" |
| Notes: | "MedlineMurphy, Cheryl A Stacey, Norm E eng Research Support, Non-U.S. Gov't 2002/10/09 Horm Behav. 2002 Sep; 42(2):109-15. doi: 10.1006/hbeh.2002.1810" |
