| Title: | Non-targeted analysis of unknown volatile chemicals in medical masks |
| Author(s): | Liu Y; Wang Z; Wang W; Xing J; Zhang Q; Ma Q; Lv Q; |
| Address: | "Key Laboratory of Consumer Product Quality Safety Inspection and Risk Assessment for State Market Regulation, Institute of Industrial and Consumer Product Safety, Chinese Academy of Inspection and Quarantine, Beijing 100176, China. Thermo Fisher Scientific, Beijing 100102, China. Key Laboratory of Consumer Product Quality Safety Inspection and Risk Assessment for State Market Regulation, Institute of Industrial and Consumer Product Safety, Chinese Academy of Inspection and Quarantine, Beijing 100176, China. Electronic address: Lvqing2009@126.com" |
| DOI: | 10.1016/j.envint.2022.107122 |
| ISSN/ISBN: | 1873-6750 (Electronic) 0160-4120 (Linking) |
| Abstract: | "This paper reports the non-targeted analysis of unknown volatile chemicals in medical masks through headspace gas chromatography-Orbitrap high-resolution mass spectrometry. In view of the difficulties that may be encountered in the qualitative analysis of unknown substances, several typical cases and the corresponding reliable solutions are given from the perspective of comprehensive score and retention index, chemical ionization identification molecular formula, fragment ion detail comparison for distinguishing isomers, and identification of alkanes. With this method, 69 volatile substances were identified in 60 masks. The identified substances were divided into nine categories. Alkanes, esters, benzenes, and alcohols were the top four groups of substances identified in masks and accounted for 34.8%, 15.9%, 10.1%, and 7.2% of the total substances, respectively. In addition, ketones, ethers, phenolics, amides, and other substances were identified. Ethanol, 1,4-dichlorobenzene, toluene, m-xylene, dimethyl glutarate, and N,N-dimethylacetamide had high detection rates. The identified substances were further filtered and screened according to their detection rate, toxicity, and response intensity. Finally, 12 high-risk volatile chemicals in medical masks were listed. This study could serve as a reference for identifying unknown substances and a guide for monitoring volatile chemicals in masks and promoting chemical safety improvements in products" |
| Keywords: | Alcohols Esters/analysis Gas Chromatography-Mass Spectrometry/methods *Masks *Volatile Organic Compounds/analysis Gas chromatography Medical masks Non-target Orbitrap Volatile chemicals; |
| Notes: | "MedlineLiu, Yahui Wang, Zhijuan Wang, Wan Xing, Jiangtao Zhang, Qing Ma, Qiang Lv, Qing eng Research Support, Non-U.S. Gov't Netherlands 2022/02/06 Environ Int. 2022 Mar; 161:107122. doi: 10.1016/j.envint.2022.107122. Epub 2022 Feb 2" |
