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Sci Total Environ

Title:		Cancer incidence in a petrochemical industry area in Sweden
Author(s):		Axelsson G; Barregard L; Holmberg E; Sallsten G;
Address:		"Department of Occupational and Environmental Medicine, University of Gothenburg, Sweden. gosta.axelsson@amm.gu.se"
Journal Title:		Sci Total Environ
Year:		2010
Volume:		408
Issue:		20
Page Number:		4482 - 4487
DOI:		10.1016/j.scitotenv.2010.06.028
ISSN/ISBN:		1879-1026 (Electronic) 0048-9697 (Linking)
Abstract:		"Emissions from petrochemical industries may contain suspected or established carcinogens. As increased incidence of cancer in residential areas close to petrochemical industries has been reported in the literature, we conducted a study of cancer incidence in Stenungsund, Sweden, where petrochemical industries were established in the mid 1960s. A number of cancer cases in the central parts of Stenungsund were collected from the regional cancer registry for each year between 1974 and 2005. In addition to the total number of cases, the numbers of leukemia, lymphoma, liver cancer, lung cancer, and brain cancer were also collected. Expected numbers for each year were calculated based on age- and sex-specific incidence rates in reference areas. Levels of carcinogenic volatile hydrocarbons (VOC) were estimated from measurements and emission data. A dispersion model was used to classify Stenungsund into a 'low' and 'high' ethylene level area. Standardized Incidence Ratio (SIR) for all cancer for the entire period was 1.02 (95% CI 0.97-1.08). The occurrence of leukemia, lymphoma, and cancer in the central nervous system was slightly lower than expected for the entire period. SIR for lung cancer was 1.37 (95% CI 1.10-1.69), and SIR for liver cancer was 1.50 (0.82-2.53). VOC levels were low. Taking estimated exposure and demographic factors into account, our assessment is that occurrence of cancer was not affected by industrial emissions in any of the studied sites"
Keywords:		Air Pollutants/*analysis Alkenes/analysis Benzene/analysis Butadienes/analysis *Chemical Industry Environmental Exposure/analysis/statistics & numerical data Environmental Monitoring Epidemiological Monitoring Ethylene Dichlorides/analysis Ethylenes/analy;
Notes:		"MedlineAxelsson, Gosta Barregard, Lars Holmberg, Erik Sallsten, Gerd eng Research Support, Non-U.S. Gov't Netherlands 2010/07/14 Sci Total Environ. 2010 Sep 15; 408(20):4482-7. doi: 10.1016/j.scitotenv.2010.06.028"