| Title: | Anopheles gambiae s.l. swarms trapping as a complementary tool against residual malaria transmission in eastern Gambia |
| Author(s): | Assogba BS; Sillah S; Opondo KO; Cham ST; Camara MM; Jadama L; Camara L; Ndiaye A; Wathuo M; Jawara M; Diabate A; Achan J; D'Alessandro U; |
| Address: | "Disease Control and Elimination Theme, Medical Research Council, Unit The Gambia at London School of Hygiene and Tropical Medicine, PO Box 273, Banjul, The Gambia. Sessinou-Benoit.Assogba@lshtm.ac.uk. Disease Control and Elimination Theme, Medical Research Council, Unit The Gambia at London School of Hygiene and Tropical Medicine, PO Box 273, Banjul, The Gambia. Laboratoire d'Ecologie Vectorielle et Parasitaire, Faculte des Sciences et Techniques, Universite Cheikh Anta Diop, Dakar, Senegal. Statistic and Bioinformatic Department, Medical Research Council, Unit The Gambia at London School of Hygiene and Tropical Medicine, PO Box 273, Banjul, The Gambia. Institut de Recherche en Science de la Sante/Centre Muraz, BP 545, Bobo-Dioulasso, Burkina Faso. Disease Control and Elimination Theme, Medical Research Council, Unit The Gambia at London School of Hygiene and Tropical Medicine, PO Box 273, Banjul, The Gambia. Umberto.Dalessandro@lshtm.ac.uk" |
| DOI: | 10.1038/s41598-022-21577-7 |
| ISSN/ISBN: | 2045-2322 (Electronic) 2045-2322 (Linking) |
| Abstract: | "Malaria remains a major health problem and vector control is an essential approach to decrease its burden, although it is threatened by insecticide resistance. New approaches for vector control are needed. The females of Anopheles gambiae s.l. mate once in their life and in the swarms formed by males. Trapping swarms of Anopheles gambiae s.l. males is a potential new intervention for vector control, alternative to the use of insecticides, as it would disrupt mating . The proof-of-concept pilot study aiming at investigating swarm trapping as a potential vector control intervention, was carried out in 6 villages as in eastern Gambia. Swarms of Anopheles gambiae s.l. were identified and their size, height, and duration determined during the baseline year. Swarm trapping by local volunteers was implemented the following transmission season in 4 villages while the other 2 villages were taken as controls. Entomological outcomes were monitored by Human Landing Catches and Pyrethrum Spray Catches. A cross-sectional survey to determine malaria prevalence was carried out at the peak of the malaria transmission season for two consecutive years. At baseline, 23 swarming sites of Anopheles gambiae s.l. were identified. Before the intervention, mean indoor resting density per house and malaria prevalence were similar between control and intervention villages. Following the intervention, Anopheles gambiae s.l. indoor resting density was 44% lower in intervention than in control villages (adj IRR: 0.0.56; 95% CI 0.47-0.68); the odds of malaria infections were 68% lower in intervention than in control villages (OR: 0.32; 95% CI 0.11-0.97). Swarm trapping seems to be a promising, community-based vector control intervention that could reduce malaria prevalence by reducing vector density. Such results should be further investigated and confirmed by larger cluster-randomized trials" |
| Keywords: | Animals *Anopheles Cross-Sectional Studies Female Gambia/epidemiology Humans *Insecticides/pharmacology *Malaria/epidemiology/prevention & control Male Mosquito Control/methods Mosquito Vectors Pilot Projects; |
| Notes: | "MedlineAssogba, Benoit Sessinou Sillah, Salimina Opondo, Kevin O Cham, Sheikh Tijan Camara, Muhammed M Jadama, Lamin Camara, Lamin Ndiaye, Assane Wathuo, Miriam Jawara, Musa Diabate, Abdoulaye Achan, Jane D'Alessandro, Umberto eng 107741/A/15/Z/WT_/Wellcome Trust/United Kingdom Research Support, Non-U.S. Gov't England 2022/10/13 Sci Rep. 2022 Oct 12; 12(1):17057. doi: 10.1038/s41598-022-21577-7" |
