| Title: | "Cedrol, a malaria mosquito oviposition attractant is produced by fungi isolated from rhizomes of the grass Cyperus rotundus" |
| Author(s): | Eneh LK; Saijo H; Borg-Karlson AK; Lindh JM; Rajarao GK; |
| Address: | "Chemical Ecology Unit, Division of Organic Chemistry, KTH Royal Institute of Technology, Stockholm, Sweden. Forest Products Group, Faculty of Agriculture, Yamagata University, Tsuruoka, Japan. Chemical Ecology Unit, Division of Organic Chemistry, KTH Royal Institute of Technology, Stockholm, Sweden. jenlindh@kth.se. Division of Industrial Biotechnology, School of Biotechnology, KTH Royal Institute of Technology, Stockholm, Sweden" |
| DOI: | 10.1186/s12936-016-1536-7 |
| ISSN/ISBN: | 1475-2875 (Electronic) 1475-2875 (Linking) |
| Abstract: | "BACKGROUND: Cedrol, a sesquiterpene alcohol, is the first identified oviposition attractant for African malaria vectors. Finding the natural source of this compound might help to elucidate why Anopheles gambiae and Anopheles arabiensis prefer to lay eggs in habitats containing it. Previous studies suggest that cedrol may be a fungal metabolite and the essential oil of grass rhizomes have been described to contain a high amount of different sesquiterpenes. RESULTS: Rhizomes of the grass Cyperus rotundus were collected in a natural malaria mosquito breeding site. Two fungi were isolated from an aqueous infusion with these rhizomes. They were identified as Fusarium falciforme and a species in the Fusarium fujikuroi species complex. Volatile compounds were collected from the headspace above fungal cultures on Tenax traps which were analysed by gas chromatography-mass spectrometry (GCMS). Cedrol and a cedrol isomer were detected in the headspace above the F. fujikuroi culture, while only cedrol was detected above the F. falciforme culture. CONCLUSION: Cedrol an oviposition attractant for African malaria vectors is produced by two fungi species isolated from grass rhizomes collected from a natural mosquito breeding site" |
| Keywords: | Animals Anopheles/*drug effects/physiology Cyperus/*microbiology Female Fusarium/classification/isolation & purification/*metabolism Gas Chromatography-Mass Spectrometry Mosquito Vectors/*drug effects/physiology Oviposition/*drug effects/physiology Pherom; |
| Notes: | "MedlineEneh, Lynda K Saijo, Hiromi Borg-Karlson, Anna-Karin Lindh, Jenny M Rajarao, Gunaratna Kuttuva eng R01 AI082537/AI/NIAID NIH HHS/ England 2016/09/19 Malar J. 2016 Sep 17; 15:478. doi: 10.1186/s12936-016-1536-7" |
