« Previous AbstractApplication of soil in forensic science: residual odor and HRD dogs    Next Abstract"The Effect of Wind Speed on Male Potato Aphid, Macrosiphum euphorbiae, Responses to Primary Host Plant Volatiles and Female Sex Pheromone" »

Br J Pharmacol

Title:		THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: G protein-coupled receptors
Author(s):		Alexander SPH; Christopoulos A; Davenport AP; Kelly E; Mathie A; Peters JA; Veale EL; Armstrong JF; Faccenda E; Harding SD; Pawson AJ; Sharman JL; Southan C; Davies JA; Collaborators C;
Address:		"School of Life Sciences, University of Nottingham Medical School, Nottingham, NG7 2UH, UK. Monash Institute of Pharmaceutical Sciences and Department of Pharmacology, Monash University, Parkville, Victoria, 3052, Australia. Clinical Pharmacology Unit, University of Cambridge, Cambridge, CB2 0QQ, UK. School of Physiology, Pharmacology and Neuroscience, University of Bristol, Bristol, BS8 1TD, UK. Medway School of Pharmacy, The Universities of Greenwich and Kent at Medway, Anson Building, Central Avenue, Chatham Maritime, Chatham, Kent, ME4 4TB, UK. Neuroscience Division, Medical Education Institute, Ninewells Hospital and Medical School, University of Dundee, Dundee, DD1 9SY, UK. Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, EH8 9XD, UK"
Journal Title:		Br J Pharmacol
Year:		2019
Volume:		176 Suppl 1
Issue:		Suppl 1
Page Number:		S21 - S141
DOI:		10.1111/bph.14748
ISSN/ISBN:		1476-5381 (Electronic) 0007-1188 (Print) 0007-1188 (Linking)
Abstract:		"The Concise Guide to PHARMACOLOGY 2019/20 is the fourth in this series of biennial publications. The Concise Guide provides concise overviews of the key properties of nearly 1800 human drug targets with an emphasis on selective pharmacology (where available), plus links to the open access knowledgebase source of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. Although the Concise Guide represents approximately 400 pages, the material presented is substantially reduced compared to information and links presented on the website. It provides a permanent, citable, point-in-time record that will survive database updates. The full contents of this section can be found at http://onlinelibrary.wiley.com/doi/10.1111/bph.14748. G protein-coupled receptors are one of the six major pharmacological targets into which the Guide is divided, with the others being: ion channels, nuclear hormone receptors, catalytic receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The landscape format of the Concise Guide is designed to facilitate comparison of related targets from material contemporary to mid-2019, and supersedes data presented in the 2017/18, 2015/16 and 2013/14 Concise Guides and previous Guides to Receptors and Channels. It is produced in close conjunction with the International Union of Basic and Clinical Pharmacology Committee on Receptor Nomenclature and Drug Classification (NC-IUPHAR), therefore, providing official IUPHAR classification and nomenclature for human drug targets, where appropriate"
Keywords:		"Animals Databases, Pharmaceutical Humans Ligands Pharmaceutical Preparations/*chemistry Receptors, G-Protein-Coupled/*agonists/chemistry/metabolism;"
Notes:		"MedlineAlexander, Stephen P H Christopoulos, Arthur Davenport, Anthony P Kelly, Eamonn Mathie, Alistair Peters, John A Veale, Emma L Armstrong, Jane F Faccenda, Elena Harding, Simon D Pawson, Adam J Sharman, Joanna L Southan, Christopher Davies, Jamie A eng G0900805/MRC_/Medical Research Council/United Kingdom MR/R008167/1/MRC_/Medical Research Council/United Kingdom R01 NS103940/NS/NINDS NIH HHS/ Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Review England 2019/11/12 Br J Pharmacol. 2019 Dec; 176 Suppl 1(Suppl 1):S21-S141. doi: 10.1111/bph.14748"