| Title: | A sexual rejection peptide: potential use for controlling mouse overpopulation |
| Author(s): | Osakada T; Itakura T; Kenmochi R; Touhara K; |
| Address: | "a Department of Applied Biological Chemistry , Graduate School of Agricultural and Life Sciences, The University of Tokyo , Tokyo , Japan. b ERATO Touhara Chemosensory Signal Project, JST , The University of Tokyo , Tokyo , Japan. c International Research Center for Neurointelligence (WPI-IRCN) , The University of Tokyo Institutes for Advanced Study , Tokyo , Japan" |
| Journal Title: | Biosci Biotechnol Biochem |
| DOI: | 10.1080/09168451.2018.1554427 |
| ISSN/ISBN: | 1347-6947 (Electronic) 0916-8451 (Linking) |
| Abstract: | "Exocrine gland-secreting peptide 22 (ESP22) is a 10-kDa protein secreted in tears of juvenile mice. ESP22 inhibits sexual behaviors in adults, leading to a reduction in reproduction rate. We herein identified the 24 amino acid sequence within ESP22 that was essential for exhibiting sexual rejection activity. This synthesizable peptide can be useful for controlling mouse overpopulation" |
| Keywords: | "Amino Acid Sequence Animals Female Gene Expression Intercellular Signaling Peptides and Proteins Male Mice Mice, Inbred C57BL Olfactory Bulb/cytology/drug effects/physiology Pheromones/biosynthesis/chemistry/*genetics/pharmacology Population Control/*meth;" |
| Notes: | "MedlineOsakada, Takuya Itakura, Takumi Kenmochi, Ryo Touhara, Kazushige eng England 2018/12/06 Biosci Biotechnol Biochem. 2019 Apr; 83(4):705-708. doi: 10.1080/09168451.2018.1554427. Epub 2018 Dec 5" |
