Title: | Ru-catalyzed decarbonylative addition of aliphatic aldehydes to terminal alkynes |
Address: | "Department of Chemistry, McGill University, 801 Sherbrooke St. West, Montreal, Quebec H3A 2K6, Canada" |
ISSN/ISBN: | 1523-7052 (Electronic) 1523-7052 (Linking) |
Abstract: | "A novel method for the formation of isolated C=C bonds was developed via a ruthenium-catalyzed decarbonylative addition of aliphatic aldehydes and alkynes. An unprecedented complete switch of chemoselectivity from aromatic aldehydes to aliphatic aldehydes was observed simply by using tri(2,4,6-trismethoxyphenyl)phosphine as ligand. A synthesis by this method of an insect sex pheromone was demonstrated" |
Keywords: | Aldehydes/*chemistry Alkenes/chemistry Alkynes/*chemistry Catalysis Ruthenium/*chemistry Substrate Specificity; |
Notes: | "MedlineGuo, Xiangyu Wang, Jun Li, Chao-Jun eng Research Support, Non-U.S. Gov't 2010/06/17 Org Lett. 2010 Jul 16; 12(14):3176-8. doi: 10.1021/ol101107w" |