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Science

Title:		Pheromone-induced changes in the acidophil concentration of mouse pituitary glands
Author(s):		Avery TL;
Address:
Journal Title:		Science
Year:		1969
Volume:		164
Issue:		3878
Page Number:		423 - 424
DOI:		10.1126/science.164.3878.423
ISSN/ISBN:		0036-8075 (Print) 0036-8075 (Linking)
Abstract:		Pituitaries of female mice in anestrus resulting from colony housing were characterized by a 58.0-percent (acidophil content. Subsequent exposure to restrained male mice for one and two nights failed to evoke significant acidophilic degranulation and resulted in pituitary acidophil values of 57.4 and 55.1 percent respectively. Exposure to released males on the third night produced marked acidophilic degranulation resulting in a significant decline in pituitary acidophils to 38.0 percent. These findings support the view that female pheromone suppresses and male pheromone favors the secretion of follicle-stimulating hormone and indicate that luteotrophic hormone is secreted at its assigned time in the sequence of cyclic ovarian events initiated by the secretion of follicle-stimulating hormone
Keywords:		"Animals Cytoplasmic Granules Estrus Female Follicle Stimulating Hormone/*metabolism Luteinizing Hormone/*metabolism Male Mice Pheromones/*pharmacology Pituitary Gland/*cytology/drug effects/metabolism Pregnancy Prolactin/metabolism Stimulation, Chemical;"
Notes:		"MedlineAvery, T L eng 1969/04/25 Science. 1969 Apr 25; 164(3878):423-4. doi: 10.1126/science.164.3878.423"