| Title: | Developments in the Catalytic Asymmetric Synthesis of Agrochemicals and Their Synthetic Importance |
| Author(s): | Sharma SK; Paniraj ASR; Tambe YB; |
| Address: | "Rallis Research Centre, No. 73/1C and 73/1D, Byregowda Industrial Estate, Srigandhanagar, Hegganhalli, Bangalore 560091, Karnataka, India" |
| ISSN/ISBN: | 1520-5118 (Electronic) 0021-8561 (Linking) |
| Abstract: | "Catalytic asymmetric synthesis has become an essential tool for the enantioselective synthesis of pharmaceuticals, natural products, and agrochemicals (mainly fungicides, herbicides, insecticides, and pheromones). With continuous growing interest in both modern agricultural chemistry and catalytic asymmetric synthesis chemistry, this review provides a comprehensive overview of some earlier reports as well as the recent successful applications of various catalytic asymmetric syntheses methodologies, such as enantioselective hydroformylation, enantioselective hydrogenation, asymmetric Sharpless epoxidation and dihydroxylation, asymmetric cyclopropanation or isomerization, organocatalyzed asymmetric synthesis, and so forth, which have been used as key steps in the preparation of chiral agrochemicals (on R&D, piloting, and commercial scales). Chiral agrochemicals can also lead the new generation of such chemicals having specific and novel modes of action for achieving sustainable crop protection and production. Some perspectives and challenges for these catalytic asymmetric methodologies in the synthesis of chiral agrochemicals are also briefly discussed in the final section of the manuscript. This review will provide the insight regarding understanding, development, and evaluation of catalytic asymmetric systems for the synthesis of chiral agrochemicals among the agrochemists" |
| Keywords: | "Agrochemicals *Biological Products Catalysis Crop Protection *Fungicides, Industrial catalytic asymmetric synthesis chiral enantioselective herbicides insecticides pheromones;" |
| Notes: | "MedlineSharma, Sandeep Kumar Paniraj, Alilugatta Sheshagiri Rao Tambe, Yashwant Bhikaji eng Review 2021/12/02 J Agric Food Chem. 2021 Dec 15; 69(49):14761-14780. doi: 10.1021/acs.jafc.1c05553. Epub 2021 Nov 30" |
