| Title: | The Chemical Diversity of the Ascomycete Fungus Paecilomyces variotii |
| Author(s): | Mioso R; Toledo Marante FJ; Herrera Bravo de Laguna I; |
| Address: | "Department of Biochemistry, Federal University of Pernambuco - UFPE, Recife, Pernambuco, 50740-465, Brazil. Department of Chemistry, University of Las Palmas de Gran Canaria - ULPGC, 35017, Las Palmas de Gran Canaria, Spain. Department of Biology, University of Las Palmas de Gran Canaria - ULPGC, 35017, Las Palmas de Gran Canaria, Spain. ictiocentauros@hotmail.com" |
| DOI: | 10.1007/s12010-015-1783-z |
| ISSN/ISBN: | 1559-0291 (Electronic) 0273-2289 (Linking) |
| Abstract: | "Paecilomyces variotii isolated from a broad range of habitats drives the diversification of new high-value-added secondary metabolites that could potentially play an important role in human and animal health. These metabolites include the anhydride metabolite of the nonadride family, as well as the following compounds: naphthopyranone metabolites, sphingofungins, eicosenoic acids, new branched fatty acids, ascofuranone, polyketides, an anacardic acid analogue, straight-chain peptides, and volatile compounds. These natural products show that P. variotii can provide leading compounds for new drug discoveries, which may include herbicide agents, some of which are important in the agrochemical market. Finally, this review outlines recent developments, trends, and prospects for the chemistry of this ascomycete" |
| Keywords: | Animals Biological Products/chemistry/metabolism Humans Organic Chemicals/chemistry/metabolism Paecilomyces/*chemistry/metabolism Bioactive compounds Byssochlamys spectabilis Fungus Paecilomyces variotii Secondary metabolites; |
| Notes: | "MedlineMioso, Roberto Toledo Marante, Francisco Javier Herrera Bravo de Laguna, Irma eng Review 2015/08/20 Appl Biochem Biotechnol. 2015 Oct; 177(4):781-91. doi: 10.1007/s12010-015-1783-z. Epub 2015 Aug 19" |
