« Previous AbstractGas chromatography/olfactometry and electronic nose analyses of retronasal aroma of espresso and correlation with sensory evaluation by an artificial neural network    Next Abstract"Characterisation of nano- and micron-sized airborne and collected subway particles, a multi-analytical approach" »

Biochim Biophys Acta

Title:		Involvement of gap junctional communication in secretion
Author(s):		Michon L; Nlend Nlend R; Bavamian S; Bischoff L; Boucard N; Caille D; Cancela J; Charollais A; Charpantier E; Klee P; Peyrou M; Populaire C; Zulianello L; Meda P;
Address:		"Department of Cell Physiology and Metabolism, University of Geneva, C.M.U., 1 rue Michel Servet, 1211 Geneva 4, Switzerland"
Journal Title:		Biochim Biophys Acta
Year:		2005
Volume:		20051118
Issue:		1-Feb
Page Number:		82 - 101
DOI:		10.1016/j.bbamem.2005.11.003
ISSN/ISBN:		0006-3002 (Print) 0006-3002 (Linking)
Abstract:		"Glands were the first type of tissues in which the permissive role of gap junctions in the cell-to-cell transfer of membrane-impermeant molecules was shown. During the 40 years that have followed this seminal finding, gap junctions have been documented in all types of multicellular secretory systems, whether of the exocrine, endocrine or pheromonal nature. Also, compelling evidence now indicates that gap junction-mediated coupling, and/or the connexin proteins per se, play significant regulatory roles in various aspects of gland functions, ranging from the biosynthesis, storage and release of a variety of secretory products, to the control of the growth and differentiation of secretory cells, and to the regulation of gland morphogenesis. This review summarizes this evidence in the light of recent reports"
Keywords:		"Animals Calcium/metabolism *Cell Communication Cell Membrane/metabolism Connexins/metabolism/*physiology Endocrine Glands/*metabolism Exocrine Glands/*metabolism Gap Junctions/*physiology Humans Models, Biological Protein Isoforms Signal Transduction Tiss;"
Notes:		"MedlineMichon, Laetitia Nlend Nlend, Rachel Bavamian, Sabine Bischoff, Lorraine Boucard, Nathalie Caille, Dorothee Cancela, Jose Charollais, Anne Charpantier, Eric Klee, Philippe Peyrou, Manon Populaire, Celine Zulianello, Laurence Meda, Paolo eng 1R01 DK-63443-01/DK/NIDDK NIH HHS/ Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Review Netherlands 2005/12/20 Biochim Biophys Acta. 2005 Dec 20; 1719(1-2):82-101. doi: 10.1016/j.bbamem.2005.11.003. Epub 2005 Nov 18"