| Title: | "Characterization of a peptide from skin secretions of male specimens of the frog, Leptodactylus fallax that stimulates aggression in male frogs" |
| Author(s): | King JD; Rollins-Smith LA; Nielsen PF; John A; Conlon JM; |
| Address: | "Department of Biology, University of Missouri-St. Louis, St. Louis, MO 63121, USA" |
| DOI: | 10.1016/j.peptides.2004.11.004 |
| ISSN/ISBN: | 0196-9781 (Print) 0196-9781 (Linking) |
| Abstract: | "During the breeding season of the mountain chicken frog Leptodactylus fallax, fighting between males results in the emergence of dominant animals that subsequently attract females to nesting sites. A peptide, termed Leptodactylus aggression-stimulating peptide (LASP), was isolated from norepinephrine-stimulated skin secretions from male specimens of L. fallax that was not present in skin secretions obtained from females. The primary structure of the peptide was established as: Gly-Leu-Trp-Asp-Asp-Leu-Lys-Ala-Ala-Ala-Lys-Lys-Val-Val-Ser-Ser-Leu-Ala-Ser-Ala-Ala-Ile-Glu-Lys-Leu NH2. LASP had no pheromone-like action on females but had a chemoattractive effect on males and stimulated aggressive behaviors, such as rearing and leaping. It is suggested that this peptide may play an important role in initiating the competitive male-male interactions that are associated with the onset of reproductive behavior in L. fallax" |
| Keywords: | "*Aggression Amino Acid Sequence Animals Anura Chromatography, High Pressure Liquid Female Male Peptides/chemistry/isolation & purification/*metabolism/physiology Sexual Behavior, Animal Skin/*metabolism;" |
| Notes: | "MedlineKing, Jay D Rollins-Smith, Louise A Nielsen, Per F John, Anne Conlon, J Michael eng Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. 2005/03/09 Peptides. 2005 Apr; 26(4):597-601. doi: 10.1016/j.peptides.2004.11.004. Epub 2004 Dec 10" |
