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Biochim Biophys Acta Rev Cancer

Title:		Ability of animals to detect cancer odors
Author(s):		Gouzerh F; Ganem G; Pichevin A; Dormont L; Thomas F;
Address:		"Centre de Recherches Ecologiques et Evolutives sur le Cancer, Maladies Infectieuses et Vecteurs: Ecologie, Genetique, Evolution et Controle, UMR IRD 224- CNRS 5290- Universite de Montpellier, 34394 Montpellier, France; Centre d'Ecologie Fonctionnelle et Evolutive, Universite?n de Montpellier, CNRS, EPHE, IRD, Universite Paul Valery Montpellier 3, 34293 Montpellier, France. Electronic address: flora.gouzerh@ird.fr. Institut des Sciences de l'Evolution, ISEM, Universite Montpellier, CNRS, IRD, 34095 Montpellier, France. Centre d'Ecologie Fonctionnelle et Evolutive, Universite?n de Montpellier, CNRS, EPHE, IRD, Universite Paul Valery Montpellier 3, 34293 Montpellier, France. Centre de Recherches Ecologiques et Evolutives sur le Cancer, Maladies Infectieuses et Vecteurs: Ecologie, Genetique, Evolution et Controle, UMR IRD 224- CNRS 5290- Universite de Montpellier, 34394 Montpellier, France"
Journal Title:		Biochim Biophys Acta Rev Cancer
Year:		2023
Volume:		20221214
Issue:		1
Page Number:		188850 -
DOI:		10.1016/j.bbcan.2022.188850
ISSN/ISBN:		1879-2561 (Electronic) 0304-419X (Linking)
Abstract:		"The olfactory capacity of animals has long been used by humans to help with various activities, e.g., hunting, detecting mines, locating people, and diagnosing diseases. Cancer is among the leading diseases causing death worldwide. Several recent studies have underscored the benefit of using scent to detect cancer, and this paper will review the studies using animals to detect tumor scents. A large variety of animals have been used for this purpose-dogs, rodents, insects, and nematodes-and have shown their capacity to detect cancer, with a success rate close to 90%. Here we discuss these studies, their methodologies, and the animal models used. Finally, we discuss the medical perspectives for cancer diagnosis using odors"
Keywords:		"Humans Animals Dogs *Odorants Smell *Neoplasms/diagnosis Models, Animal Behavioral response Cancer odor Odor discrimination Olfactory sensor Volatile organic compounds;"
Notes:		"MedlineGouzerh, Flora Ganem, Guila Pichevin, Anais Dormont, Laurent Thomas, Frederic eng Research Support, Non-U.S. Gov't Review Netherlands 2022/12/18 Biochim Biophys Acta Rev Cancer. 2023 Jan; 1878(1):188850. doi: 10.1016/j.bbcan.2022.188850. Epub 2022 Dec 14"