« Previous AbstractEffect on embryos of injection of phosphorothioate-modified oligonucleotides into pregnant mice    Next AbstractComparison of the efficacy of a synthetic dog-appeasing pheromone with clomipramine for the treatment of separation-related disorders in dogs »

Mar Biotechnol (NY)

Title:		Identification of a New Set of Polypeptidic Sex Pheromones from Cuttlefish (Sepia officinalis)
Author(s):		Gaudin-Zatylny C; Corre E; Zanuttini B; Endress M; Bernay B; Pontin J; Leduc A; Henry J;
Address:		"Laboratoire de Biologie Des Organismes Et Ecosystemes Aquatiques (BOREA), Universite de Caen-Normandie, MNHN, SU, UA, CNRS, IRD-207, 14 000, Caen, France. Normandie Univ, UNICAEN, UMR 8067 BOREA, MNHN, SU, UA, CNRS, IRD-207, 14 000, Caen, France. CNRS, Sorbonne Universite, R242429680, ABiMS, Station Biologique, 29680, Roscoff, France. Normandie Univ, UNICAEN, ENSICAEN, CNRS, GREYC, 14 000, Caen, France. Laboratoire de Biologie Des Organismes Et Ecosystemes Aquatiques (BOREA), Universite de Caen-Normandie, MNHN, SU, UA, CNRS, IRD-207, 14 000, Caen, France. joel.henry@unicaen.fr. Normandie Univ, UNICAEN, UMR 8067 BOREA, MNHN, SU, UA, CNRS, IRD-207, 14 000, Caen, France. joel.henry@unicaen.fr. Normandie Univ, UNICAEN, ENSICAEN, CNRS, GREYC, 14 000, Caen, France. joel.henry@unicaen.fr. Normandie Univ, UNICAEN, SF ICORE 4206, US EMerode, Proteogen plateform, 14000, Caen, France. joel.henry@unicaen.fr"
Journal Title:		Mar Biotechnol (NY)
Year:		2022
Volume:		20220409
Issue:		3
Page Number:		574 - 587
DOI:		10.1007/s10126-022-10126-y
ISSN/ISBN:		1436-2236 (Electronic) 1436-2228 (Linking)
Abstract:		"The common English Channel cuttlefish (Sepia officinalis) reproduces every year on very localized coastal spawning areas after a west-east horizontal migration of several tens of kilometers (80-200 km). The massive arrival of spawners on the coasts of west Cotentin and the Bay of Seine is suspected to be driven by the action of sex pheromones expressed and secreted by the genitals of sexually mature females. The present study aims to verify the existence of polypeptide pheromones, of a higher molecular weight than those described above. Their size could confer them a wider range of action than that of the previously identified peptide pheromones. The implementation of an experimental strategy combining transcriptomics and proteomics with functional tests and an in silico study led to the identification of a cocktail of pheromones with molecular weights ranging between 22 and 26 kDa. Proteomic analyses combined to functional tests revealed partial pheromone release in the environment, and their accumulation in the outer capsule of the egg, suggesting the eggs as pheromone diffusers, also able to induce stimulation by contact when the eggs are handled by females"
Keywords:		Animals Decapodiformes Female Peptides Proteomics *Sepia/physiology *Sex Attractants Cephalopod Oviduct gland Reproduction Sepia officinalis Sex pheromones;
Notes:		"MedlineGaudin-Zatylny, Celine Corre, Erwan Zanuttini, Bruno Endress, Maxime Bernay, Benoit Pontin, Julien Leduc, Alexandre Henry, Joel eng 2022/04/10 Mar Biotechnol (NY). 2022 Jun; 24(3):574-587. doi: 10.1007/s10126-022-10126-y. Epub 2022 Apr 9"