| Title: | Evaluation of multiple solid-phase microextraction as a technique to remove the matrix effect in packaging analysis for determination of volatile organic compounds |
| Author(s): | Ezquerro O; Pons B; Tena MT; |
| Address: | "Department of Chemistry, University of La Rioja, C/Madre de Dios 51, E-26006 Logrono (La Rioja), Spain" |
| DOI: | 10.1016/j.chroma.2003.08.066 |
| ISSN/ISBN: | 0021-9673 (Print) 0021-9673 (Linking) |
| Abstract: | "Multiple solid-phase microextraction (SPME) is an useful technique for the direct quantification of solid samples removing any matrix effect. The volatile organic compounds formed in the extrusion-coating process of multilayer packaging materials have already been quantified by multiple HS-SPME coupled to gas chromatography (GC)-mass spectrometry (MS) using volatile organic compound (VOC) solutions in hexadecane for calibration. In this article, water is proposed as solvent to prepare the calibration solutions because it provides a shorter calibration time, better linearity, better reproducibility, and lower detection limits than hexadecane. Besides, the extraction of VOCs from aqueous solutions is exhaustive and avoids the extrapolations needed to calculate the total peak areas, as they can be calculated as the sum of the individual areas of each extraction. Finally, it is checked whether the two solvents provide the same mean values for the total peak areas" |
| Keywords: | Gas Chromatography-Mass Spectrometry/*methods Organic Chemicals/*analysis Volatilization; |
| Notes: | "MedlineEzquerro, Oscar Pons, Begona Tena, Maria Teresa eng Evaluation Study Research Support, Non-U.S. Gov't Netherlands 2003/12/10 J Chromatogr A. 2003 Dec 12; 1020(2):189-97. doi: 10.1016/j.chroma.2003.08.066" |
