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J Chromatogr A

Title:		Head space solid phase microextraction based on nano-structured lead dioxide: application to the speciation of volatile organoselenium in environmental and biological samples
Author(s):		Ghasemi E; Farahani H;
Address:		"Department of Chemistry, Pharmaceutical Sciences Branch, Islamic Azad University, Tehran, Iran. ghasemi.e@iaups.ac.ir"
Journal Title:		J Chromatogr A
Year:		2012
Volume:		20120815
Issue:
Page Number:		16 - 20
DOI:		10.1016/j.chroma.2012.08.027
ISSN/ISBN:		1873-3778 (Electronic) 0021-9673 (Linking)
Abstract:		"A novel and efficient speciation method based on the nano-structured lead dioxide as stationary phase of head space solid phase microextraction combined with gas chromatography mass spectrometry (GC-MS) was developed for the determination of volatile organoselenium compounds (dimethylselenide (DMSe) and dimethyldiselenide (DMDSe)) in different biological and environmental samples. PbO(2) particles with a diameter in the range of 50-70 nm have been grown on platinum wire via elechtrochemical deposition. The effect of different variables on the extraction efficiency was studied simultaneously using an experimental design. The variables of interest in the HS-SPME were condition of coating preparation, desorption time, stirring rate, desorption temperature, ionic strength, time and temperature of extraction. A Plackett-Burman design was performed for screening in order to determine the significant variables affecting the extraction efficiency. Then, the significant factors were optimized by a Box-Behnken design (BBD) and the response surface equations were derived. The detection limit and relative standard deviation (RSD) (n=5, c=50 mugL(-1)) for DMSe were 16 ngL(-1) and 4.3%, respectively. They were also obtained for DMDSe as 11ngL(-1) and 4.6%, respectively. The developed technique was found to be applicable to spiked environmental and biological samples"
Keywords:		Animals Beverages/analysis Environmental Pollutants/analysis Fruit/chemistry Humans Lead/*chemistry Limit of Detection Metal Nanoparticles/*chemistry Milk/chemistry Organoselenium Compounds/*analysis/blood/isolation & purification/urine Oxides/*chemistry;
Notes:		"MedlineGhasemi, Ensieh Farahani, Hadi eng Netherlands 2012/09/04 J Chromatogr A. 2012 Oct 5; 1258:16-20. doi: 10.1016/j.chroma.2012.08.027. Epub 2012 Aug 15"