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Gac Sanit

Title:		[Air pollutant exposure during pregnancy and fetal and early childhood development. Research protocol of the INMA (Childhood and Environment Project)]
Author(s):		Esplugues A; Fernandez-Patier R; Aguilera I; Iniguez C; Garcia Dos Santos S; Aguirre Alfaro A; Lacasana M; Estarlich M; Grimalt JO; Fernandez M; Rebagliato M; Sala M; Tardon A; Torrent M; Martinez MD; Ribas-Fito N; Sunyer J; Ballester F;
Address:		"Escola Valenciana d'Estudis en Salut (EVES), Valencia, Espana. Hospital Universitari La Fe, Valencia, Espana"
Journal Title:		Gac Sanit
Year:		2007
Volume:		21
Issue:		2
Page Number:		162 - 171
DOI:		10.1157/13101050
ISSN/ISBN:		0213-9111 (Print) 0213-9111 (Linking)
Abstract:		"INTRODUCTION: The INMA (INfancia y Medio Ambiente [Spanish for Environment and Childhood]) project is a cooperative research network. This project aims to study the effects of environment and diet on fetal and early childhood development. This article aims to present the air pollutant exposure protocol during pregnancy and fetal and early childhood development of the INMA project. METHODS: The information to assess air pollutant exposure during pregnancy is based on outdoor measurement of air pollutants (nitrogen dioxide [NO2], volatile organic compounds [VOC], ozone, particulate matter [PM10, PM2,5 ] and of their composition [polycyclic aromatic hydrocarbons]); measurement of indoor and personal exposure (VOC and NO2); urinary measurement of a biological marker of hydrocarbon exposure (1-hydroxypyrene); and data gathered by questionnaires and geographic information systems. These data allow individual air pollutant exposure indexes to be developed, which can then be used to analyze the possible effects of exposure on fetal development and child health. CONCLUSION: This protocol and the type of study allow an approximation to individual air pollutant exposure to be obtained. Finally, the large number of participants (N = 4,000), as well as their geographic and social diversity, increases the study's potential"
Keywords:		"Air Pollution/*analysis *Child Development Child, Preschool Female *Fetal Development Humans Infant Infant, Newborn Inhalation Exposure/*analysis Maternal Exposure/*adverse effects Pregnancy;"
Notes:		"MedlineEsplugues, Ana Fernandez-Patier, Rosalia Aguilera, Inma Iniguez, Carmen Garcia Dos Santos, Saul Aguirre Alfaro, Amelia Lacasana, Marina Estarlich, Marisa Grimalt, Joan O Fernandez, Marieta Rebagliato, Marisa Sala, Maria Tardon, Adonina Torrent, Maties Martinez, Maria Dolores Ribas-Fito, Nuria Sunyer, Jordi Ballester, Ferran spa English Abstract Research Support, Non-U.S. Gov't Spain 2007/04/11 Gac Sanit. 2007 Mar-Apr; 21(2):162-71. doi: 10.1157/13101050"