Title: | Acute effects of some volatile organic compounds emitted from water-based paints |
Author(s): | Ernstgard L; Lof A; Wieslander G; Norback D; Johanson G; |
Address: | "Work Environment Toxicology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden. Lena.Ernstgard@ki.se" |
DOI: | 10.1097/JOM.0b013e3181161ced |
ISSN/ISBN: | 1536-5948 (Electronic) 1076-2752 (Linking) |
Abstract: | "OBJECTIVE: Acute effects during controlled exposure to some of the volatile organic compounds emitted from water-based paints were evaluated. METHODS: Healthy volunteers (10 atopics, 10 nonatopics, and 10 painters) were exposed to a mixture of propyleneglycol, texanol, diethyleneglycol monoethylether, diethyleneglycol monobutyl ether, and dipropyleneglycol monomethyl ether at a total concentration of 35 mg/m3 (G), a mixture of G and ammonia (15 mg/m3) (GA), and clean air (C). RESULTS: Subjective ratings of irritation in eyes, nose, throat, and dyspnea were significantly higher during the G and GA conditions, when compared with during the C condition. Nasal mucosal swelling was observed after G but not after GA exposure. No effects of the exposure on the pulmonary function, markers of inflammation in nasal lavages, and renal function in urine were seen. CONCLUSION: Exposure to G and GA caused mild irritation in eyes, nose, and airways" |
Keywords: | "Adult Air Pollution, Indoor/adverse effects/analysis Humans Inhalation Exposure/*adverse effects Irritants/analysis/toxicity Male Middle Aged Occupational Exposure/*adverse effects Organic Chemicals/analysis/*toxicity Paint/*toxicity Respiration Disorders;" |
Notes: | "MedlineErnstgard, Lena Lof, Agneta Wieslander, Gunilla Norback, Dan Johanson, Gunnar eng Research Support, Non-U.S. Gov't 2007/08/19 J Occup Environ Med. 2007 Aug; 49(8):880-9. doi: 10.1097/JOM.0b013e3181161ced" |